Increased serum HMGB1 levels in patients with Henoch-Schönlein purpura

High‐mobility group box‐1 (HMGB1) has been implicated as a pro‐inflammatory cytokine in the pathogenesis of various inflammatory and autoimmune diseases. However, information about HMGB1 in Henoch–Schönlein purpura (HSP) is still unclear. Herein, we investigated the role of HMGB1 in patients with HS...

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Veröffentlicht in:	Experimental dermatology 2014-06, Vol.23 (6), p.419-423
Hauptverfasser:	Chen, Tao, Guo, Zai-pei, Wang, Wen-ju, Qin, Sha, Cao, Na, Li, Meng-meng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biomarkers - blood Case-Control Studies Cells, Cultured Child cytokine Dose-Response Relationship, Drug endothelial cells Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Female Henoch-Schönlein purpura High-mobility group box-1 HMGB1 Protein - blood HMGB1 Protein - pharmacology HMGB1 Protein - physiology Humans Interleukin-6 - metabolism Male NF-kappa B - metabolism Purpura, Schoenlein-Henoch - blood Purpura, Schoenlein-Henoch - etiology Purpura, Schoenlein-Henoch - physiopathology Tumor Necrosis Factor-alpha - metabolism Urticaria - blood Vasculitis, Leukocytoclastic, Cutaneous - blood Young Adult
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