Lower extremity salvage complicated by recurrent microvascular thrombosis in a patient with congenital factor VII deficiency

Because we could not identify any other cases of microvascular surgery in patients with Factor VII deficiency, we provided a review of the diagnosis and treatment guidelines in the hypercoagulable patient. [...]of the extensive softtissue defect with exposure of bone and hardware in the distal third of the leg, limb reconstruction necessitated free tissue transfer and a free anterolateral fasciocutaneous flap from the contralateral leg was undertaken using the anterior tibial artery and vein as recipient vessels.