1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs. Inactivation of monoamine oxidase by conformationally rigid analogs of N,N-dimethylcinnamylamine

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a potent neurotoxin and also an inactivator of monoamine oxidase (MAO). Since MPTP is a conformationally rigid analogue of N,N-dimethylcinnamylamine, other conformationally rigid analogues of N,N-dimethylcinnamylamine were synthesized and tested...

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