Effects of age, gender and region on serum concentrations of perfluorinated compounds in general population of Henan, China
•133 Serum samples were collected from inland China aged 0–88years for analysis.•Compared with coastal region, the levels and composition of PFCs were different.•Significant increases in PFOA, PFNA, and PFOS concentrations over age were found.•Median concentrations of 4 PFCs were higher in males tha...
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| Veröffentlicht in: | Chemosphere (Oxford) 2014-09, Vol.110, p.104-110 |
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| creator | Fu, Yaning Wang, Tieyu Wang, Pei Fu, Quanliang Lu, Yonglong |
| description | •133 Serum samples were collected from inland China aged 0–88years for analysis.•Compared with coastal region, the levels and composition of PFCs were different.•Significant increases in PFOA, PFNA, and PFOS concentrations over age were found.•Median concentrations of 4 PFCs were higher in males than in females.•Higher PFOA concentrations were found in urban populations.
133 Serum samples collected from Henan donors aged from 0 to 88years were analyzed for 12 perfluorinated compounds (PFCs). Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) accounted for 69.19% of the total PFCs in serum samples, with a median concentration of 1.43 and 1.47ngmL−1, respectively. Other PFCs were detected at much lower concentrations, with median concentrations ranging from 0.03 to 0.37ngmL−1. PFOA and PFOS were positively correlated (r=0.219) in serum samples, indicating that they may have common exposure pathways. For all donors (0–88years), significant increases in PFOA (r=0.239, p |
| doi_str_mv | 10.1016/j.chemosphere.2014.02.020 |
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133 Serum samples collected from Henan donors aged from 0 to 88years were analyzed for 12 perfluorinated compounds (PFCs). Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) accounted for 69.19% of the total PFCs in serum samples, with a median concentration of 1.43 and 1.47ngmL−1, respectively. Other PFCs were detected at much lower concentrations, with median concentrations ranging from 0.03 to 0.37ngmL−1. PFOA and PFOS were positively correlated (r=0.219) in serum samples, indicating that they may have common exposure pathways. For all donors (0–88years), significant increases in PFOA (r=0.239, p<0.01), perfluorononanoic acid (PFNA) (r=0.185, p<0.05) and PFOS (r=0.175, p<0.05) concentrations over age were found. Median concentrations of PFOA, PFNA, perfluorodecanoic acid (PFDA), and PFOS were higher in males than in females. Higher PFOA concentrations were found in urban populations than in rural populations. Since PFCs exposure in general population is prevalent, further studies are needed to explore its possible impacts on epidemiological factors.</description><identifier>ISSN: 0045-6535</identifier><identifier>EISSN: 1879-1298</identifier><identifier>DOI: 10.1016/j.chemosphere.2014.02.020</identifier><identifier>PMID: 24630253</identifier><identifier>CODEN: CMSHAF</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Age Factors ; Air. Soil. Water. Waste. Feeding ; Alkanesulfonic Acids - blood ; Biological and medical sciences ; Caprylates - blood ; Chemical and industrial products toxicology. Toxic occupational diseases ; Child, Preschool ; China ; Decanoic Acids - blood ; Environment. Living conditions ; Environmental Pollutants - blood ; Female ; Fluorocarbons - blood ; General population ; Henan ; Humans ; Infant ; Male ; Medical sciences ; Middle Aged ; Perfluorinated compound ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Serum ; Sex Factors ; Toxicology ; Urban Population ; Various organic compounds ; Young Adult</subject><ispartof>Chemosphere (Oxford), 2014-09, Vol.110, p.104-110</ispartof><rights>2014 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c598t-dcd9fa5422ddb55a912a168ebf7ea1688b074bd57aa86314d1b43aaed95eb493</citedby><cites>FETCH-LOGICAL-c598t-dcd9fa5422ddb55a912a168ebf7ea1688b074bd57aa86314d1b43aaed95eb493</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.chemosphere.2014.02.020$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28506839$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24630253$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fu, Yaning</creatorcontrib><creatorcontrib>Wang, Tieyu</creatorcontrib><creatorcontrib>Wang, Pei</creatorcontrib><creatorcontrib>Fu, Quanliang</creatorcontrib><creatorcontrib>Lu, Yonglong</creatorcontrib><title>Effects of age, gender and region on serum concentrations of perfluorinated compounds in general population of Henan, China</title><title>Chemosphere (Oxford)</title><addtitle>Chemosphere</addtitle><description>•133 Serum samples were collected from inland China aged 0–88years for analysis.•Compared with coastal region, the levels and composition of PFCs were different.•Significant increases in PFOA, PFNA, and PFOS concentrations over age were found.•Median concentrations of 4 PFCs were higher in males than in females.•Higher PFOA concentrations were found in urban populations.
133 Serum samples collected from Henan donors aged from 0 to 88years were analyzed for 12 perfluorinated compounds (PFCs). Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) accounted for 69.19% of the total PFCs in serum samples, with a median concentration of 1.43 and 1.47ngmL−1, respectively. Other PFCs were detected at much lower concentrations, with median concentrations ranging from 0.03 to 0.37ngmL−1. PFOA and PFOS were positively correlated (r=0.219) in serum samples, indicating that they may have common exposure pathways. For all donors (0–88years), significant increases in PFOA (r=0.239, p<0.01), perfluorononanoic acid (PFNA) (r=0.185, p<0.05) and PFOS (r=0.175, p<0.05) concentrations over age were found. Median concentrations of PFOA, PFNA, perfluorodecanoic acid (PFDA), and PFOS were higher in males than in females. Higher PFOA concentrations were found in urban populations than in rural populations. Since PFCs exposure in general population is prevalent, further studies are needed to explore its possible impacts on epidemiological factors.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Air. Soil. Water. Waste. Feeding</subject><subject>Alkanesulfonic Acids - blood</subject><subject>Biological and medical sciences</subject><subject>Caprylates - blood</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Child, Preschool</subject><subject>China</subject><subject>Decanoic Acids - blood</subject><subject>Environment. Living conditions</subject><subject>Environmental Pollutants - blood</subject><subject>Female</subject><subject>Fluorocarbons - blood</subject><subject>General population</subject><subject>Henan</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Perfluorinated compound</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Serum</subject><subject>Sex Factors</subject><subject>Toxicology</subject><subject>Urban Population</subject><subject>Various organic compounds</subject><subject>Young Adult</subject><issn>0045-6535</issn><issn>1879-1298</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU2LFDEQhoMo7rj6FyQeBA_bY5JOejpHGVZXWPCy91CdVM9k6E7apFuQ_fOmd8aPo1CQEJ6nqnhDyDvOtpzx5uNpa484xjwdMeFWMC63TJRiz8iGtztdcaHb52TDmFRVo2p1RV7lfGKsyEq_JFdCNjUTqt6Qx9u-RztnGnsKB7yhBwwOE4XgaMKDj4GWypiWkdoYLIY5wVyen4wJUz8sMfkAM7oCjFNcgsvUh7URJhjoFKdleFJW4w4DhBu6PxblNXnRw5DxzeW8Jg-fbx_2d9X9ty9f95_uK6t0O1fOOt2DkkI41ykFmgvgTYtdv8P10nZsJzundgBtU3PpeCdrAHRaYSd1fU0-nNtOKX5fMM9m9NniMEDAuGTDVc21aqSQBdVn1KaYc8LeTMmPkH4azswavTmZf6I3a_SGiVKsuG8vY5ZuRPfH_J11Ad5fAMgWhj5BsD7_5VrFmrZe992fOSyZ_PCYTLYeS_TOp_JVxkX_H-v8Ar4bqmg</recordid><startdate>20140901</startdate><enddate>20140901</enddate><creator>Fu, Yaning</creator><creator>Wang, Tieyu</creator><creator>Wang, Pei</creator><creator>Fu, Quanliang</creator><creator>Lu, Yonglong</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140901</creationdate><title>Effects of age, gender and region on serum concentrations of perfluorinated compounds in general population of Henan, China</title><author>Fu, Yaning ; Wang, Tieyu ; Wang, Pei ; Fu, Quanliang ; Lu, Yonglong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c598t-dcd9fa5422ddb55a912a168ebf7ea1688b074bd57aa86314d1b43aaed95eb493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Air. Soil. Water. Waste. Feeding</topic><topic>Alkanesulfonic Acids - blood</topic><topic>Biological and medical sciences</topic><topic>Caprylates - blood</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Child, Preschool</topic><topic>China</topic><topic>Decanoic Acids - blood</topic><topic>Environment. Living conditions</topic><topic>Environmental Pollutants - blood</topic><topic>Female</topic><topic>Fluorocarbons - blood</topic><topic>General population</topic><topic>Henan</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Perfluorinated compound</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Serum</topic><topic>Sex Factors</topic><topic>Toxicology</topic><topic>Urban Population</topic><topic>Various organic compounds</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fu, Yaning</creatorcontrib><creatorcontrib>Wang, Tieyu</creatorcontrib><creatorcontrib>Wang, Pei</creatorcontrib><creatorcontrib>Fu, Quanliang</creatorcontrib><creatorcontrib>Lu, Yonglong</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chemosphere (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fu, Yaning</au><au>Wang, Tieyu</au><au>Wang, Pei</au><au>Fu, Quanliang</au><au>Lu, Yonglong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of age, gender and region on serum concentrations of perfluorinated compounds in general population of Henan, China</atitle><jtitle>Chemosphere (Oxford)</jtitle><addtitle>Chemosphere</addtitle><date>2014-09-01</date><risdate>2014</risdate><volume>110</volume><spage>104</spage><epage>110</epage><pages>104-110</pages><issn>0045-6535</issn><eissn>1879-1298</eissn><coden>CMSHAF</coden><abstract>•133 Serum samples were collected from inland China aged 0–88years for analysis.•Compared with coastal region, the levels and composition of PFCs were different.•Significant increases in PFOA, PFNA, and PFOS concentrations over age were found.•Median concentrations of 4 PFCs were higher in males than in females.•Higher PFOA concentrations were found in urban populations.
133 Serum samples collected from Henan donors aged from 0 to 88years were analyzed for 12 perfluorinated compounds (PFCs). Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) accounted for 69.19% of the total PFCs in serum samples, with a median concentration of 1.43 and 1.47ngmL−1, respectively. Other PFCs were detected at much lower concentrations, with median concentrations ranging from 0.03 to 0.37ngmL−1. PFOA and PFOS were positively correlated (r=0.219) in serum samples, indicating that they may have common exposure pathways. For all donors (0–88years), significant increases in PFOA (r=0.239, p<0.01), perfluorononanoic acid (PFNA) (r=0.185, p<0.05) and PFOS (r=0.175, p<0.05) concentrations over age were found. Median concentrations of PFOA, PFNA, perfluorodecanoic acid (PFDA), and PFOS were higher in males than in females. Higher PFOA concentrations were found in urban populations than in rural populations. Since PFCs exposure in general population is prevalent, further studies are needed to explore its possible impacts on epidemiological factors.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>24630253</pmid><doi>10.1016/j.chemosphere.2014.02.020</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Age Factors Air. Soil. Water. Waste. Feeding Alkanesulfonic Acids - blood Biological and medical sciences Caprylates - blood Chemical and industrial products toxicology. Toxic occupational diseases Child, Preschool China Decanoic Acids - blood Environment. Living conditions Environmental Pollutants - blood Female Fluorocarbons - blood General population Henan Humans Infant Male Medical sciences Middle Aged Perfluorinated compound Public health. Hygiene Public health. Hygiene-occupational medicine Serum Sex Factors Toxicology Urban Population Various organic compounds Young Adult |
| title | Effects of age, gender and region on serum concentrations of perfluorinated compounds in general population of Henan, China |
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