Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types

Endoplasmic reticulum (ER) stress plays an essential role in unfolded protein response induced apoptosis contributing to several pathological conditions. Glycogen synthase kinase-3β (GSK-3β) plays a central role in several apoptotic signaling, including ER stress, as the active form of GSK-3β induce...

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Veröffentlicht in:	Apoptosis (London) 2014-07, Vol.19 (7), p.1080-1098
Hauptverfasser:	Balogh, András, Németh, Mária, Koloszár, Ibolya, Markó, Lajos, Przybyl, Lukasz, Jinno, Kazushi, Szigeti, Csilla, Heffer, Marija, Gebhardt, Matthias, Szeberényi, József, Müller, Dominik N., Sétáló, György, Pap, Marianna
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Apoptosis - drug effects Biochemistry Biomedical and Life Sciences Biomedicine Cancer Research Cell Biology Cell Line Cell Survival Cyclic AMP Response Element-Binding Protein - genetics Cyclic AMP Response Element-Binding Protein - metabolism Endoplasmic Reticulum Stress Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - metabolism Glycogen Synthase Kinase 3 - metabolism Glycogen Synthase Kinase 3 beta Lithium Microtubules - metabolism Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Mutation Oncology Organ Specificity Original Paper PC12 Cells Rats Tunicamycin - pharmacology Virology
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