An aptamer-based quartz crystal microbalance biosensor for sensitive and selective detection of leukemia cells using silver-enhanced gold nanoparticle label

An aptamer-based quartz crystal microbalance (QCM) biosensor was developed for the selective and sensitive detection of leukemia cells. In this strategy, aminophenylboronic acid-modified gold nanoparticles (APBA-AuNPs) which could bind to cell membrane were used for the labeling of cells followed by...

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Veröffentlicht in:	Talanta (Oxford) 2014-08, Vol.126, p.130-135
Hauptverfasser:	Shan, Wenqian, Pan, Yuliang, Fang, Heting, Guo, Manli, Nie, Zhou, Huang, Yan, Yao, Shouzhuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminophenylboronic acid (APBA) Aptamers, Nucleotide - chemistry Aptamers, Nucleotide - metabolism Binding, Competitive Biosensing Techniques - instrumentation Biosensing Techniques - methods Cell Adhesion Cell Line, Tumor Cell Separation - instrumentation Cell Separation - methods Gold - chemistry Gold - metabolism Gold nanoparticles (AuNPs) Humans Leukemia cell detection Metal Nanoparticles - chemistry Microscopy, Fluorescence Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology Quartz crystal microbalance (QCM) Quartz Crystal Microbalance Techniques - methods Reproducibility of Results Silver - chemistry Silver - metabolism Silver enhancement
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