Action of a thionin isolated from nuts of Pyrularia pubera on human erythrocytes

— Pyrularia thionin is a strongly basic peptide of 47 amino acids isolated from Pyrularia pubera. This peptide, a member of the thionin family, is hemolytic, cytotoxic and neurotoxic. The characteristics of the hemolytic activity on human erythrocytes are as follows: (1) the peptide does not itself...

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Veröffentlicht in:	Toxicon (Oxford) 1989, Vol.27 (5), p.501-510
Hauptverfasser:	Osorio e Castro, V.R., Van Kuiken, Barbara A., Vernon, Leo P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial Cationic Peptides binding sites Biological and medical sciences Calcium - pharmacology erythrocytes Erythrocytes - drug effects Hemolysis Humans In Vitro Techniques isolation Kinetics Medical sciences nuts Nuts - analysis peptides Phospholipases A - metabolism Phospholipases A2 Plant poisons toxicology Plant Proteins - antagonists & inhibitors Plant Proteins - isolation & purification Plant Proteins - toxicity Santalaceae Toxicology
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