Continuous cocrystallisation of carbamazepine and trans-cinnamic acid viamelt extrusion processing

A solvent free process for the formation of carbamazepine (CBZ)-trans-cinnamic acid (TCA) cocrystals, in stoichiometric ratios, was developed using continuous hot melt extrusion processing. Physicochemical characterization of the CBZ-TCA extrudates included scanning electron microscopy (SEM), differ...

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Veröffentlicht in:	CrystEngComm 2014-03, Vol.16 (17), p.3573-3583
Hauptverfasser:	Moradiya, Hiren G, Islam, Muhammad T, Halsey, Sheelagh, Maniruzzaman, Mohammed, Chowdhry, Babur Z, Snowden, Martin J, Douroumis, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystallinity Differential scanning calorimetry Diffraction Extrusion Melts Prototypes Scanning electron microscopy Solvents
Online-Zugang:	Volltext
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