Nanonization of poorly water-soluble drug clobetasone butyrate by using femtosecond laser

Nanonization, which involves the formation of the drug with nanometer particle size, is an effective method to improve the dissolution rate and bioavailability of poorly water-soluble drugs. A pulsewidth-tunable femtosecond laser was used to produce nanoparticles of clobetasone butyrate using poloxa...

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Veröffentlicht in:	Optics communications 2014-02, Vol.313, p.152-156
Hauptverfasser:	Pan, Sunqiang, Takebe, Gen, Suzuki, Masumi, Takamoto, Hisayoshi, Ge, Jianhong, Liu, Chong, Hiramatsu, Mitsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Drugs Femtosecond Femtosecond laser Lasers Monolayers Nanonization Nanoparticle Nanoparticles Nanostructure Particle size Permeability Poorly water-soluble drug
Online-Zugang:	Volltext
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