Genipin crosslinking elevates the strength of electrochemically aligned collagen to the level of tendons

Collagen-based tissue mimics are important in clinical research because collagen is the main structural element in tendons. The current study aimed to improve the mechanical strength of Electronically Aligned Collagen (ELAC) threads by optimizing several crosslinking parameters. The results indicate...

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Veröffentlicht in:	Journal of the mechanical behavior of biomedical materials 2012-11, Vol.15, p.176-189
Hauptverfasser:	Alfredo Uquillas, Jorge, Kishore, Vipuil, Akkus, Ozan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alignment Biomechanical Phenomena Biomimetic Materials - chemistry Biomimetic Materials - pharmacology Cell Adhesion - drug effects Cell Proliferation - drug effects Collagen - chemistry Collagen - pharmacology Collagens Crosslinking Electrochemically aligned collagen Electrochemistry Ethanol Ethanol - chemistry Ethyl alcohol Genipin Human mesenchymal stem cell mechanical properties Humans Iridoids - chemistry Mechanical Phenomena Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Strength Tendons Time Factors Tissue engineering
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