DNA methylation detection by a novel fluorimetric nanobiosensor for early cancer diagnosis

A very sensitive and convenient fluorescence nanobiosensor for rapid detection of DNA methylation based on Fe3O4/Au core/shell nanoparticles has been developed. Specific site of CpG islands of adenomatous polyposis coli (APC), a well studied tumor suppressor gene, was used as the detection target DN...

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Veröffentlicht in:	Biosensors & bioelectronics 2014-10, Vol.60, p.35-44
Hauptverfasser:	Dadmehr, M., Hosseini, M., Hosseinkhani, S., Ganjali, M.R., Khoobi, M., Behzadi, H., Hamedani, M., Sheikhnejad, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biosensing Techniques - instrumentation Biotechnology Dipyridamole DNA methylation DNA Methylation - genetics DNA, Neoplasm - analysis DNA, Neoplasm - chemistry DNA, Neoplasm - genetics Early Detection of Cancer - instrumentation Equipment Design Equipment Failure Analysis Fe@Au nanoparticle Fluorescence Fluorometry - instrumentation Fundamental and applied biological sciences. Psychology Humans Nanobiosensor Nanotechnology - instrumentation Neoplasms - diagnosis Neoplasms - genetics Reproducibility of Results Sensitivity and Specificity Sequence Analysis, DNA - instrumentation
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