Increased CXCL9 serum levels in hepatitis C-related mixed cryoglobulinemia, with autoimmune thyroiditis, associated with high levels of CXCL10

Increased CXCL9 serum levels in hepatitis C-related mixed cryoglobulinemia, with autoimmune thyroiditis, associated with high levels of CXCL10

Until now, no study has evaluated CXCL9 in hepatitis C virus (HCV) infection-related mixed cryoglobulinemia (MC) patients in presence/absence of autoimmune thyroiditis (AT). Serum CXCL9 and CXCL10 have been measured in 60 patients with MC (MCo), in 35 patients with MC and AT (MC-AT), in sex and age-...

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Veröffentlicht in:Journal of interferon & cytokine research 2013-12, Vol.33 (12), p.739-745
Hauptverfasser: Antonelli, Alessandro, Fallahi, Poupak, Ferrari, Silvia Martina, Colaci, Michele, Giuggioli, Dilia, Saraceno, Giovanna, Benvenga, Salvatore, Ferri, Clodoveo
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Case-Control Studies
Chemokine CXCL10 - blood
Chemokine CXCL9 - blood
Cryoglobulinemia - blood
Cryoglobulinemia - complications
Cryoglobulinemia - diagnosis
Female
Hepatitis C - complications
Hepatitis C virus
Humans
Male
Middle Aged
Thyroid Gland - physiopathology
Thyroiditis, Autoimmune - blood
Thyroiditis, Autoimmune - complications
Thyroiditis, Autoimmune - diagnosis
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Zusammenfassung:Until now, no study has evaluated CXCL9 in hepatitis C virus (HCV) infection-related mixed cryoglobulinemia (MC) patients in presence/absence of autoimmune thyroiditis (AT). Serum CXCL9 and CXCL10 have been measured in 60 patients with MC (MCo), in 35 patients with MC and AT (MC-AT), in sex and age-matched controls: 60 healthy (Control 1); 35 patients with AT without cryoglobulinemia (Control 2). CXCL9 and CXCL10 were higher in MC-AT patients than Control 2 (P
ISSN:1079-9907
1557-7465
DOI:10.1089/jir.2012.0091