Direct Oral Anticoagulants—Interference With Laboratory Tests and Mechanism of Action

Direct oral anticoagulants (DOACs) have been established and already registered for clinical use on a wide basis in the United States and Europe. Different from the vitamin K antagonists (VKA), their mode of action is based on the direct inhibition of the single coagulation enzymes factor Xa or IIa....

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Veröffentlicht in:	Seminars in hematology 2014-04, Vol.51 (2), p.98-101
1. Verfasser:	Tsakiris, Dimitrios A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Anticoagulants - administration & dosage Anticoagulants - chemistry Anticoagulants - metabolism Drug Interactions Drug Monitoring Factor Xa - metabolism Factor Xa Inhibitors Hematology, Oncology and Palliative Medicine Humans Partial Thromboplastin Time Prothrombin - antagonists & inhibitors Prothrombin - metabolism Prothrombin Time Thromboembolism - prevention & control
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