An improved method for the characterization of supersaturation and precipitation of poorly soluble drugs using pulsatile microdialysis (PMD)
[Display omitted] In current pharmaceutical drug discovery, most candidates are poorly soluble in water, which can result in poor bioavailability. To overcome this problem, formulations that create supersaturation of the drug are a well-studied alternative. Characterizing the dissolution from these...
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Veröffentlicht in: | International journal of pharmaceutics 2014-07, Vol.468 (1-2), p.64-74 |
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Format: | Artikel |
Sprache: | eng |
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