Structural Studies of the Capsular Polysaccharide From S. pneumoniae Type 12F

Structural Studies of the Capsular Polysaccharide From S. pneumoniae Type 12F

The capsular polysaccharide from S. pneumoniae type 12F is composed of D-glucosyl, D-galactosyl, 2-acetamido-2-deoxy-D-galactosyl, 2-acetamido-2,6-dideoxy-L-galactosyl, and 2-acetamido-2-deoxy-D-mannuronic acid residues in the proportions 2:1:1:1:1. The main structural evidence was adduced from nmr...

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Veröffentlicht in:Canadian journal of chemistry 1981-01, Vol.59 (14), p.2081-2085
Hauptverfasser: Leontein, K, Lindberg, B, Loenngren, J
Format: Artikel
Sprache:eng
Schlagworte:
Streptococcus pneumoniae
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Zusammenfassung:The capsular polysaccharide from S. pneumoniae type 12F is composed of D-glucosyl, D-galactosyl, 2-acetamido-2-deoxy-D-galactosyl, 2-acetamido-2,6-dideoxy-L-galactosyl, and 2-acetamido-2-deoxy-D-mannuronic acid residues in the proportions 2:1:1:1:1. The main structural evidence was adduced from nmr spectroscopy, methylation analysis, and specific degradations whereby it could be concluded that the polysaccharide is composed of hexasaccharide repeating-units.
ISSN:0008-4042