Heart disease in pregnancy: Ischaemic heart disease
Coronary artery disease and in particular acute coronary syndromes in pregnancy are increasing with high risk of mortality and significant morbidity. Whilst women with atherosclerotic risk factors are at greater risk of developing problems in pregnancy, it is important to remember that women can dev...
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Veröffentlicht in: | Best practice & research. Clinical obstetrics & gynaecology 2014-05, Vol.28 (4), p.551-562 |
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container_title | Best practice & research. Clinical obstetrics & gynaecology |
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creator | Fryearson, John, MBChB, MRCP Adamson, Dawn L., BSc (Hons), MBBS, MRCP, PhD |
description | Coronary artery disease and in particular acute coronary syndromes in pregnancy are increasing with high risk of mortality and significant morbidity. Whilst women with atherosclerotic risk factors are at greater risk of developing problems in pregnancy, it is important to remember that women can develop problems even in the absence of atherosclerosis—secondary to thrombosis or coronary dissection. A low threshold to investigate women with chest pain is paramount, and women with raised troponin levels should be investigated seriously. Acute coronary syndromes should be managed using an invasive strategy where possible and women should not have coronary angiography withheld for fear of foetal harm. This article aims to review the limited available data of coronary artery disease in pregnancy and give practical advice on the management of stable and acute coronary disease, with particular emphasis on the latter. |
doi_str_mv | 10.1016/j.bpobgyn.2014.03.011 |
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Whilst women with atherosclerotic risk factors are at greater risk of developing problems in pregnancy, it is important to remember that women can develop problems even in the absence of atherosclerosis—secondary to thrombosis or coronary dissection. A low threshold to investigate women with chest pain is paramount, and women with raised troponin levels should be investigated seriously. Acute coronary syndromes should be managed using an invasive strategy where possible and women should not have coronary angiography withheld for fear of foetal harm. This article aims to review the limited available data of coronary artery disease in pregnancy and give practical advice on the management of stable and acute coronary disease, with particular emphasis on the latter.</description><identifier>ISSN: 1521-6934</identifier><identifier>EISSN: 1532-1932</identifier><identifier>DOI: 10.1016/j.bpobgyn.2014.03.011</identifier><identifier>PMID: 24794768</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>cardiovascular pregnancy complications ; Coronary Angiography ; Coronary Artery Bypass ; Female ; Humans ; myocardial ischaemia ; Myocardial Ischemia - diagnosis ; Myocardial Ischemia - epidemiology ; Myocardial Ischemia - etiology ; Myocardial Ischemia - therapy ; Obstetrics and Gynecology ; Pregnancy ; Pregnancy Complications, Cardiovascular - diagnosis ; Pregnancy Complications, Cardiovascular - epidemiology ; Pregnancy Complications, Cardiovascular - etiology ; Pregnancy Complications, Cardiovascular - therapy ; Risk Factors ; Stents</subject><ispartof>Best practice & research. Clinical obstetrics & gynaecology, 2014-05, Vol.28 (4), p.551-562</ispartof><rights>2014</rights><rights>Copyright © 2014. Published by Elsevier Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-a45cd8072ada7027860d728508520c99ffb1f3609f0ab03ec37812b246975beb3</citedby><cites>FETCH-LOGICAL-c420t-a45cd8072ada7027860d728508520c99ffb1f3609f0ab03ec37812b246975beb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.bpobgyn.2014.03.011$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24794768$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fryearson, John, MBChB, MRCP</creatorcontrib><creatorcontrib>Adamson, Dawn L., BSc (Hons), MBBS, MRCP, PhD</creatorcontrib><title>Heart disease in pregnancy: Ischaemic heart disease</title><title>Best practice & research. Clinical obstetrics & gynaecology</title><addtitle>Best Pract Res Clin Obstet Gynaecol</addtitle><description>Coronary artery disease and in particular acute coronary syndromes in pregnancy are increasing with high risk of mortality and significant morbidity. Whilst women with atherosclerotic risk factors are at greater risk of developing problems in pregnancy, it is important to remember that women can develop problems even in the absence of atherosclerosis—secondary to thrombosis or coronary dissection. A low threshold to investigate women with chest pain is paramount, and women with raised troponin levels should be investigated seriously. Acute coronary syndromes should be managed using an invasive strategy where possible and women should not have coronary angiography withheld for fear of foetal harm. This article aims to review the limited available data of coronary artery disease in pregnancy and give practical advice on the management of stable and acute coronary disease, with particular emphasis on the latter.</description><subject>cardiovascular pregnancy complications</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Bypass</subject><subject>Female</subject><subject>Humans</subject><subject>myocardial ischaemia</subject><subject>Myocardial Ischemia - diagnosis</subject><subject>Myocardial Ischemia - epidemiology</subject><subject>Myocardial Ischemia - etiology</subject><subject>Myocardial Ischemia - therapy</subject><subject>Obstetrics and Gynecology</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Cardiovascular - diagnosis</subject><subject>Pregnancy Complications, Cardiovascular - epidemiology</subject><subject>Pregnancy Complications, Cardiovascular - etiology</subject><subject>Pregnancy Complications, Cardiovascular - therapy</subject><subject>Risk Factors</subject><subject>Stents</subject><issn>1521-6934</issn><issn>1532-1932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcFOwzAMhiMEYjB4BFCPXFqcpGlTDiA0AZs0iQNwjtLU3TK6tiQbUt-eVhsIceFkH77flj8TckEhokCT61WUt02-6OqIAY0j4BFQekBOqOAspBlnh0PPaJhkPB6RU-9XAJxnTByTEYvTLE4TeUL4FLXbBIX1qD0Gtg5ah4ta16a7CWbeLDWurQmWv6kzclTqyuP5vo7J2-PD62Qazp-fZpP7eWhiBptQx8IUElKmC50CS2UCRcqkACkYmCwry5yWPIGsBJ0DR8NTSVnO4iRLRY45H5Or3dzWNR9b9Bu1tt5gVekam61X_XmSc8kT2qNihxrXeO-wVK2za-06RUENvtRK7X2pwZcCrnpffe5yv2Kbr7H4SX0L6oG7HYD9oZ8WnfLGYm2wsA7NRhWN_XfF7Z8JprK1Nbp6xw79qtm6ureoqPJMgXoZnjb8jMYAIITkXzYekWQ</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Fryearson, John, MBChB, MRCP</creator><creator>Adamson, Dawn L., BSc (Hons), MBBS, MRCP, PhD</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140501</creationdate><title>Heart disease in pregnancy: Ischaemic heart disease</title><author>Fryearson, John, MBChB, MRCP ; Adamson, Dawn L., BSc (Hons), MBBS, MRCP, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-a45cd8072ada7027860d728508520c99ffb1f3609f0ab03ec37812b246975beb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>cardiovascular pregnancy complications</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Bypass</topic><topic>Female</topic><topic>Humans</topic><topic>myocardial ischaemia</topic><topic>Myocardial Ischemia - diagnosis</topic><topic>Myocardial Ischemia - epidemiology</topic><topic>Myocardial Ischemia - etiology</topic><topic>Myocardial Ischemia - therapy</topic><topic>Obstetrics and Gynecology</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Cardiovascular - diagnosis</topic><topic>Pregnancy Complications, Cardiovascular - epidemiology</topic><topic>Pregnancy Complications, Cardiovascular - etiology</topic><topic>Pregnancy Complications, Cardiovascular - therapy</topic><topic>Risk Factors</topic><topic>Stents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fryearson, John, MBChB, MRCP</creatorcontrib><creatorcontrib>Adamson, Dawn L., BSc (Hons), MBBS, MRCP, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Best practice & research. 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Whilst women with atherosclerotic risk factors are at greater risk of developing problems in pregnancy, it is important to remember that women can develop problems even in the absence of atherosclerosis—secondary to thrombosis or coronary dissection. A low threshold to investigate women with chest pain is paramount, and women with raised troponin levels should be investigated seriously. Acute coronary syndromes should be managed using an invasive strategy where possible and women should not have coronary angiography withheld for fear of foetal harm. This article aims to review the limited available data of coronary artery disease in pregnancy and give practical advice on the management of stable and acute coronary disease, with particular emphasis on the latter.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>24794768</pmid><doi>10.1016/j.bpobgyn.2014.03.011</doi><tpages>12</tpages></addata></record> |
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subjects | cardiovascular pregnancy complications Coronary Angiography Coronary Artery Bypass Female Humans myocardial ischaemia Myocardial Ischemia - diagnosis Myocardial Ischemia - epidemiology Myocardial Ischemia - etiology Myocardial Ischemia - therapy Obstetrics and Gynecology Pregnancy Pregnancy Complications, Cardiovascular - diagnosis Pregnancy Complications, Cardiovascular - epidemiology Pregnancy Complications, Cardiovascular - etiology Pregnancy Complications, Cardiovascular - therapy Risk Factors Stents |
title | Heart disease in pregnancy: Ischaemic heart disease |
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