Fetal blood sampling in prenatal diagnosis of thalassemia at late pregnancy
Fetal blood sampling is a procedure that involves the drawing of a blood sample from the umbilical vein of the umbilical cord, which can be performed after 18 weeks gestation. Fetal blood sampling is a preferable method for prenatal diagnosis of thalassemia in second trimester or late pregnancy. Add...
Gespeichert in:
| Veröffentlicht in: | Journal of the Medical Association of Thailand 2014-04, Vol.97 Suppl 4, p.S49-S55 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | S55 |
|---|---|
| container_issue | |
| container_start_page | S49 |
| container_title | Journal of the Medical Association of Thailand |
| container_volume | 97 Suppl 4 |
| creator | Karnpean, Rossarin |
| description | Fetal blood sampling is a procedure that involves the drawing of a blood sample from the umbilical vein of the umbilical cord, which can be performed after 18 weeks gestation. Fetal blood sampling is a preferable method for prenatal diagnosis of thalassemia in second trimester or late pregnancy. Additionally, it is suggested to be performed in cases in which mosaicisms are identified by amniocentesis or chorionic villus sampling (CVS), areas where DNA analysis is not available, and when mutations of the parents are not known. Laboratory steps regarding prenatal diagnosis by fetal blood sampling were summarized, including the ensuring of fetal origin, determination of red blood cell parameters, fetal hemoglobin analysis, and finally fetal DNA analysis. The objective of this review is to present an overview of procedures in terms of benefits, laboratory interpretations, and some limitations. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1528336399</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1528336399</sourcerecordid><originalsourceid>FETCH-LOGICAL-p126t-fb0b1004fb1d42156a1b121cc2f264a22775c48adc641f7fc684cb45119866853</originalsourceid><addsrcrecordid>eNo1kL1OwzAYRT2AaCm8AvLIEin-jTOiigKiEgvM0WfHDkaOHWJn6NvTina6wz26OrpXaF0TKipKa7VCtzn_1DUXrWQ3aEW5EkRIsUbvO1sgYB1S6nGGcQo-DthHPM02wqnqPQwxZZ9xcrh8Q4Cc7egBQ8EBij2RQ4RoDnfo2kHI9v6cG_S1e_7cvlb7j5e37dO-mgiVpXK61uTo4jTpOT1qANGEEmOoo5IDpU0jDFfQG8mJa5yRihvNBSGtklIJtkGP_7vTnH4Xm0s3-mxsCBBtWnJHBFWMSda2R_ThjC56tH03zX6E-dBdDmB_Q5lVdg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1528336399</pqid></control><display><type>article</type><title>Fetal blood sampling in prenatal diagnosis of thalassemia at late pregnancy</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Karnpean, Rossarin</creator><creatorcontrib>Karnpean, Rossarin</creatorcontrib><description>Fetal blood sampling is a procedure that involves the drawing of a blood sample from the umbilical vein of the umbilical cord, which can be performed after 18 weeks gestation. Fetal blood sampling is a preferable method for prenatal diagnosis of thalassemia in second trimester or late pregnancy. Additionally, it is suggested to be performed in cases in which mosaicisms are identified by amniocentesis or chorionic villus sampling (CVS), areas where DNA analysis is not available, and when mutations of the parents are not known. Laboratory steps regarding prenatal diagnosis by fetal blood sampling were summarized, including the ensuring of fetal origin, determination of red blood cell parameters, fetal hemoglobin analysis, and finally fetal DNA analysis. The objective of this review is to present an overview of procedures in terms of benefits, laboratory interpretations, and some limitations.</description><identifier>ISSN: 0125-2208</identifier><identifier>PMID: 24851565</identifier><language>eng</language><publisher>Thailand</publisher><subject>Female ; Fetal Blood - chemistry ; Fetal Blood - cytology ; Fetal Diseases - blood ; Fetal Diseases - diagnosis ; Fetal Hemoglobin - analysis ; Fetal Hemoglobin - chemistry ; Humans ; Pregnancy ; Prenatal Diagnosis - methods ; Thalassemia - blood ; Thalassemia - diagnosis</subject><ispartof>Journal of the Medical Association of Thailand, 2014-04, Vol.97 Suppl 4, p.S49-S55</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24851565$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Karnpean, Rossarin</creatorcontrib><title>Fetal blood sampling in prenatal diagnosis of thalassemia at late pregnancy</title><title>Journal of the Medical Association of Thailand</title><addtitle>J Med Assoc Thai</addtitle><description>Fetal blood sampling is a procedure that involves the drawing of a blood sample from the umbilical vein of the umbilical cord, which can be performed after 18 weeks gestation. Fetal blood sampling is a preferable method for prenatal diagnosis of thalassemia in second trimester or late pregnancy. Additionally, it is suggested to be performed in cases in which mosaicisms are identified by amniocentesis or chorionic villus sampling (CVS), areas where DNA analysis is not available, and when mutations of the parents are not known. Laboratory steps regarding prenatal diagnosis by fetal blood sampling were summarized, including the ensuring of fetal origin, determination of red blood cell parameters, fetal hemoglobin analysis, and finally fetal DNA analysis. The objective of this review is to present an overview of procedures in terms of benefits, laboratory interpretations, and some limitations.</description><subject>Female</subject><subject>Fetal Blood - chemistry</subject><subject>Fetal Blood - cytology</subject><subject>Fetal Diseases - blood</subject><subject>Fetal Diseases - diagnosis</subject><subject>Fetal Hemoglobin - analysis</subject><subject>Fetal Hemoglobin - chemistry</subject><subject>Humans</subject><subject>Pregnancy</subject><subject>Prenatal Diagnosis - methods</subject><subject>Thalassemia - blood</subject><subject>Thalassemia - diagnosis</subject><issn>0125-2208</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kL1OwzAYRT2AaCm8AvLIEin-jTOiigKiEgvM0WfHDkaOHWJn6NvTina6wz26OrpXaF0TKipKa7VCtzn_1DUXrWQ3aEW5EkRIsUbvO1sgYB1S6nGGcQo-DthHPM02wqnqPQwxZZ9xcrh8Q4Cc7egBQ8EBij2RQ4RoDnfo2kHI9v6cG_S1e_7cvlb7j5e37dO-mgiVpXK61uTo4jTpOT1qANGEEmOoo5IDpU0jDFfQG8mJa5yRihvNBSGtklIJtkGP_7vTnH4Xm0s3-mxsCBBtWnJHBFWMSda2R_ThjC56tH03zX6E-dBdDmB_Q5lVdg</recordid><startdate>201404</startdate><enddate>201404</enddate><creator>Karnpean, Rossarin</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201404</creationdate><title>Fetal blood sampling in prenatal diagnosis of thalassemia at late pregnancy</title><author>Karnpean, Rossarin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-fb0b1004fb1d42156a1b121cc2f264a22775c48adc641f7fc684cb45119866853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Female</topic><topic>Fetal Blood - chemistry</topic><topic>Fetal Blood - cytology</topic><topic>Fetal Diseases - blood</topic><topic>Fetal Diseases - diagnosis</topic><topic>Fetal Hemoglobin - analysis</topic><topic>Fetal Hemoglobin - chemistry</topic><topic>Humans</topic><topic>Pregnancy</topic><topic>Prenatal Diagnosis - methods</topic><topic>Thalassemia - blood</topic><topic>Thalassemia - diagnosis</topic><toplevel>online_resources</toplevel><creatorcontrib>Karnpean, Rossarin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Medical Association of Thailand</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karnpean, Rossarin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fetal blood sampling in prenatal diagnosis of thalassemia at late pregnancy</atitle><jtitle>Journal of the Medical Association of Thailand</jtitle><addtitle>J Med Assoc Thai</addtitle><date>2014-04</date><risdate>2014</risdate><volume>97 Suppl 4</volume><spage>S49</spage><epage>S55</epage><pages>S49-S55</pages><issn>0125-2208</issn><abstract>Fetal blood sampling is a procedure that involves the drawing of a blood sample from the umbilical vein of the umbilical cord, which can be performed after 18 weeks gestation. Fetal blood sampling is a preferable method for prenatal diagnosis of thalassemia in second trimester or late pregnancy. Additionally, it is suggested to be performed in cases in which mosaicisms are identified by amniocentesis or chorionic villus sampling (CVS), areas where DNA analysis is not available, and when mutations of the parents are not known. Laboratory steps regarding prenatal diagnosis by fetal blood sampling were summarized, including the ensuring of fetal origin, determination of red blood cell parameters, fetal hemoglobin analysis, and finally fetal DNA analysis. The objective of this review is to present an overview of procedures in terms of benefits, laboratory interpretations, and some limitations.</abstract><cop>Thailand</cop><pmid>24851565</pmid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0125-2208 |
| ispartof | Journal of the Medical Association of Thailand, 2014-04, Vol.97 Suppl 4, p.S49-S55 |
| issn | 0125-2208 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1528336399 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Female Fetal Blood - chemistry Fetal Blood - cytology Fetal Diseases - blood Fetal Diseases - diagnosis Fetal Hemoglobin - analysis Fetal Hemoglobin - chemistry Humans Pregnancy Prenatal Diagnosis - methods Thalassemia - blood Thalassemia - diagnosis |
| title | Fetal blood sampling in prenatal diagnosis of thalassemia at late pregnancy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T21%3A42%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fetal%20blood%20sampling%20in%20prenatal%20diagnosis%20of%20thalassemia%20at%20late%20pregnancy&rft.jtitle=Journal%20of%20the%20Medical%20Association%20of%20Thailand&rft.au=Karnpean,%20Rossarin&rft.date=2014-04&rft.volume=97%20Suppl%204&rft.spage=S49&rft.epage=S55&rft.pages=S49-S55&rft.issn=0125-2208&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1528336399%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1528336399&rft_id=info:pmid/24851565&rfr_iscdi=true |