Effect of acute metabolic acidosis on ammonia metabolism in kidney
To understand the mechanisms that initiate the increase in ammonia formation during acute acidosis in kidney (amido- super(15)N)- and (amino- super(15)N)glutamine were used as substrates in isolated perfused rat kidney experiments. The results demonstrate that regulation of glutamine deamidation is...
Gespeichert in:
| Veröffentlicht in: | American Journal of Physiology: Cell Physiology 1989-01, Vol.256 (2), p.F321-F328 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | F328 |
|---|---|
| container_issue | 2 |
| container_start_page | F321 |
| container_title | American Journal of Physiology: Cell Physiology |
| container_volume | 256 |
| creator | Bogusky, R T Dietrich, R L |
| description | To understand the mechanisms that initiate the increase in ammonia formation during acute acidosis in kidney (amido- super(15)N)- and (amino- super(15)N)glutamine were used as substrates in isolated perfused rat kidney experiments. The results demonstrate that regulation of glutamine deamidation is an important controlling step in ammonia formation during acute metabolic acidosis in kidney. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_15281704</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>15281704</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_152817043</originalsourceid><addsrcrecordid>eNqNirsOwjAMADOARHn8gye2SikpBVZQER_AXoXUkQxJDDgd-HsYEDPT6XQ3UoU2jSmbqjYTNRW5aq3rVbMr1L71Hl0G9mDdkBEiZnvhQO7j1LOQACewMXIi-6sSgRLcqE_4mquxt0Fw8eVMLY_t-XAq709-DCi5iyQOQ7AJeZCuWq-21UbX5u_xDcVEPFI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15281704</pqid></control><display><type>article</type><title>Effect of acute metabolic acidosis on ammonia metabolism in kidney</title><source>Alma/SFX Local Collection</source><creator>Bogusky, R T ; Dietrich, R L</creator><creatorcontrib>Bogusky, R T ; Dietrich, R L</creatorcontrib><description>To understand the mechanisms that initiate the increase in ammonia formation during acute acidosis in kidney (amido- super(15)N)- and (amino- super(15)N)glutamine were used as substrates in isolated perfused rat kidney experiments. The results demonstrate that regulation of glutamine deamidation is an important controlling step in ammonia formation during acute metabolic acidosis in kidney.</description><identifier>ISSN: 0363-6143</identifier><language>eng</language><subject>acidosis ; ammonia ; glutamine</subject><ispartof>American Journal of Physiology: Cell Physiology, 1989-01, Vol.256 (2), p.F321-F328</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids></links><search><creatorcontrib>Bogusky, R T</creatorcontrib><creatorcontrib>Dietrich, R L</creatorcontrib><title>Effect of acute metabolic acidosis on ammonia metabolism in kidney</title><title>American Journal of Physiology: Cell Physiology</title><description>To understand the mechanisms that initiate the increase in ammonia formation during acute acidosis in kidney (amido- super(15)N)- and (amino- super(15)N)glutamine were used as substrates in isolated perfused rat kidney experiments. The results demonstrate that regulation of glutamine deamidation is an important controlling step in ammonia formation during acute metabolic acidosis in kidney.</description><subject>acidosis</subject><subject>ammonia</subject><subject>glutamine</subject><issn>0363-6143</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><recordid>eNqNirsOwjAMADOARHn8gye2SikpBVZQER_AXoXUkQxJDDgd-HsYEDPT6XQ3UoU2jSmbqjYTNRW5aq3rVbMr1L71Hl0G9mDdkBEiZnvhQO7j1LOQACewMXIi-6sSgRLcqE_4mquxt0Fw8eVMLY_t-XAq709-DCi5iyQOQ7AJeZCuWq-21UbX5u_xDcVEPFI</recordid><startdate>19890101</startdate><enddate>19890101</enddate><creator>Bogusky, R T</creator><creator>Dietrich, R L</creator><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope></search><sort><creationdate>19890101</creationdate><title>Effect of acute metabolic acidosis on ammonia metabolism in kidney</title><author>Bogusky, R T ; Dietrich, R L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_152817043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>acidosis</topic><topic>ammonia</topic><topic>glutamine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bogusky, R T</creatorcontrib><creatorcontrib>Dietrich, R L</creatorcontrib><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>American Journal of Physiology: Cell Physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bogusky, R T</au><au>Dietrich, R L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of acute metabolic acidosis on ammonia metabolism in kidney</atitle><jtitle>American Journal of Physiology: Cell Physiology</jtitle><date>1989-01-01</date><risdate>1989</risdate><volume>256</volume><issue>2</issue><spage>F321</spage><epage>F328</epage><pages>F321-F328</pages><issn>0363-6143</issn><abstract>To understand the mechanisms that initiate the increase in ammonia formation during acute acidosis in kidney (amido- super(15)N)- and (amino- super(15)N)glutamine were used as substrates in isolated perfused rat kidney experiments. The results demonstrate that regulation of glutamine deamidation is an important controlling step in ammonia formation during acute metabolic acidosis in kidney.</abstract></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0363-6143 |
| ispartof | American Journal of Physiology: Cell Physiology, 1989-01, Vol.256 (2), p.F321-F328 |
| issn | 0363-6143 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_15281704 |
| source | Alma/SFX Local Collection |
| subjects | acidosis ammonia glutamine |
| title | Effect of acute metabolic acidosis on ammonia metabolism in kidney |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T21%3A28%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20acute%20metabolic%20acidosis%20on%20ammonia%20metabolism%20in%20kidney&rft.jtitle=American%20Journal%20of%20Physiology:%20Cell%20Physiology&rft.au=Bogusky,%20R%20T&rft.date=1989-01-01&rft.volume=256&rft.issue=2&rft.spage=F321&rft.epage=F328&rft.pages=F321-F328&rft.issn=0363-6143&rft_id=info:doi/&rft_dat=%3Cproquest%3E15281704%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15281704&rft_id=info:pmid/&rfr_iscdi=true |