Nucleic Acid–Metal Organic Framework (MOF) Nanoparticle Conjugates

Nanoparticles of a metal–organic framework (MOF), UiO-66-N3 (Zr6O4OH4(C8H3O4–N3)6), were synthesized. The surface of the MOF was covalently functionalized with oligonucleotides, utilizing a strain promoted click reaction between DNA appended with dibenzyl­cyclo­octyne and azide-functionalized UiO-66...

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Veröffentlicht in:	Journal of the American Chemical Society 2014-05, Vol.136 (20), p.7261-7264
Hauptverfasser:	Morris, William, Briley, William E, Auyeung, Evelyn, Cabezas, Maria D, Mirkin, Chad A
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - chemistry HeLa Cells Humans Metal Nanoparticles - chemistry Models, Molecular Molecular Structure Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Particle Size Surface Properties Zirconium - chemistry
Online-Zugang:	Volltext
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