Practical synthesis of natural plant-growth regulator 2-azahypoxanthine, its derivatives, and biotin-labeled probes

We describe a practical, large-scale synthesis of the "fairy-ring" plant-growth regulator 2-azahypoxanthine (AHX), and its biologically active hydroxyl metabolite (AOH) and riboside derivative (AHXr). AHXr, a biosynthetic intermediate, was synthesized from inosine via a biomimetic route. B...

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Veröffentlicht in:	Organic & biomolecular chemistry 2014-06, Vol.12 (23), p.3813-3815
Hauptverfasser:	Ikeuchi, Kazutada, Fujii, Ryosuke, Sugiyama, Shimpei, Asakawa, Tomohiro, Inai, Makoto, Hamashima, Yoshitaka, Choi, Jae-Hoon, Suzuki, Tomohiro, Kawagishi, Hirokazu, Kan, Toshiyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes - chemistry Azides - chemistry Biotin - chemistry Chemistry, Organic - methods Hypoxanthines - chemical synthesis Hypoxanthines - chemistry Plant Growth Regulators - chemical synthesis Plant Growth Regulators - chemistry Staining and Labeling
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