Dietary aluminum and Alzheimer's disease — A review
Current evidence suggests that dietary aluminum is neither an essential nutrient nor a toxic element causing neurological damage. The phosphate and fluoride salts of aluminum are very insoluble. When fed in excess, aluminum increases the dietary needs for these anions. Aluminum hydroxide is used as...
Gespeichert in:
Veröffentlicht in: | The Science of the total environment 1981, Vol.17 (1), p.31-36 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 36 |
---|---|
container_issue | 1 |
container_start_page | 31 |
container_title | The Science of the total environment |
container_volume | 17 |
creator | Caster, W.O. Wang, Marian |
description | Current evidence suggests that dietary aluminum is neither an essential nutrient nor a toxic element causing neurological damage. The phosphate and fluoride salts of aluminum are very insoluble. When fed in excess, aluminum increases the dietary needs for these anions. Aluminum hydroxide is used as an antacid that can prevent the phosphatemia seen in severe kidney damage. In Alzheimer's disease there is progressive decrease in brain mass with the accumulation of phospholipid-rich cell debris. These membrane tangles tend to accumulate aluminum and are easily stainable with silver. |
doi_str_mv | 10.1016/0048-9697(81)90105-4 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_15270706</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0048969781901054</els_id><sourcerecordid>15270706</sourcerecordid><originalsourceid>FETCH-LOGICAL-c388t-354d9f582f1d64c55782cc90a7fcdbb2086b29d85a4267b2594f48e7c29e29733</originalsourceid><addsrcrecordid>eNp9kMtOwzAQRS0EKqXwByBlxWMRsB07tjdIVXlKldjA2nLsiTDKo9gNCFZ8BF_Il5DQqktmM4u5947uQeiQ4HOCSX6BMZOpypU4leRMYYJ5yrbQmEihUoJpvo3GG8ku2ovxBfcjJBmhkRjkSo0Rv_KwNOEjMVVX-6arE9O4ZFp9PoOvIZzExPkIJkLy8_WdTJMAbx7e99FOaaoIB-s9QU8314-zu3T-cHs_m85Tm0m5TDPOnCq5pCVxObOcC0mtVdiI0rqioFjmBVVOcsNoLgrKFSuZBGGpAqpElk3Q8Sp3EdrXDuJS1z5aqCrTQNtFTTgVWOC8F7KV0IY2xgClXgRf9700wXqgpQcUekChJdF_tDTrbUfr_K6owW1Mazz9_XJ1h75kXzzoaD00FpwPYJfatf7_B79TwHfb</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15270706</pqid></control><display><type>article</type><title>Dietary aluminum and Alzheimer's disease — A review</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Caster, W.O. ; Wang, Marian</creator><creatorcontrib>Caster, W.O. ; Wang, Marian</creatorcontrib><description>Current evidence suggests that dietary aluminum is neither an essential nutrient nor a toxic element causing neurological damage. The phosphate and fluoride salts of aluminum are very insoluble. When fed in excess, aluminum increases the dietary needs for these anions. Aluminum hydroxide is used as an antacid that can prevent the phosphatemia seen in severe kidney damage. In Alzheimer's disease there is progressive decrease in brain mass with the accumulation of phospholipid-rich cell debris. These membrane tangles tend to accumulate aluminum and are easily stainable with silver.</description><identifier>ISSN: 0048-9697</identifier><identifier>EISSN: 1879-1026</identifier><identifier>DOI: 10.1016/0048-9697(81)90105-4</identifier><identifier>PMID: 7010599</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Aluminum - adverse effects ; Aluminum - physiology ; Alzheimer Disease - etiology ; Animals ; Brain Diseases - etiology ; Dementia - etiology ; Diet - adverse effects ; Humans ; Renal Dialysis - adverse effects ; Uremia - metabolism</subject><ispartof>The Science of the total environment, 1981, Vol.17 (1), p.31-36</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-354d9f582f1d64c55782cc90a7fcdbb2086b29d85a4267b2594f48e7c29e29733</citedby><cites>FETCH-LOGICAL-c388t-354d9f582f1d64c55782cc90a7fcdbb2086b29d85a4267b2594f48e7c29e29733</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0048-9697(81)90105-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7010599$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Caster, W.O.</creatorcontrib><creatorcontrib>Wang, Marian</creatorcontrib><title>Dietary aluminum and Alzheimer's disease — A review</title><title>The Science of the total environment</title><addtitle>Sci Total Environ</addtitle><description>Current evidence suggests that dietary aluminum is neither an essential nutrient nor a toxic element causing neurological damage. The phosphate and fluoride salts of aluminum are very insoluble. When fed in excess, aluminum increases the dietary needs for these anions. Aluminum hydroxide is used as an antacid that can prevent the phosphatemia seen in severe kidney damage. In Alzheimer's disease there is progressive decrease in brain mass with the accumulation of phospholipid-rich cell debris. These membrane tangles tend to accumulate aluminum and are easily stainable with silver.</description><subject>Aluminum - adverse effects</subject><subject>Aluminum - physiology</subject><subject>Alzheimer Disease - etiology</subject><subject>Animals</subject><subject>Brain Diseases - etiology</subject><subject>Dementia - etiology</subject><subject>Diet - adverse effects</subject><subject>Humans</subject><subject>Renal Dialysis - adverse effects</subject><subject>Uremia - metabolism</subject><issn>0048-9697</issn><issn>1879-1026</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EKqXwByBlxWMRsB07tjdIVXlKldjA2nLsiTDKo9gNCFZ8BF_Il5DQqktmM4u5947uQeiQ4HOCSX6BMZOpypU4leRMYYJ5yrbQmEihUoJpvo3GG8ku2ovxBfcjJBmhkRjkSo0Rv_KwNOEjMVVX-6arE9O4ZFp9PoOvIZzExPkIJkLy8_WdTJMAbx7e99FOaaoIB-s9QU8314-zu3T-cHs_m85Tm0m5TDPOnCq5pCVxObOcC0mtVdiI0rqioFjmBVVOcsNoLgrKFSuZBGGpAqpElk3Q8Sp3EdrXDuJS1z5aqCrTQNtFTTgVWOC8F7KV0IY2xgClXgRf9700wXqgpQcUekChJdF_tDTrbUfr_K6owW1Mazz9_XJ1h75kXzzoaD00FpwPYJfatf7_B79TwHfb</recordid><startdate>1981</startdate><enddate>1981</enddate><creator>Caster, W.O.</creator><creator>Wang, Marian</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7TV</scope><scope>7U2</scope><scope>C1K</scope></search><sort><creationdate>1981</creationdate><title>Dietary aluminum and Alzheimer's disease — A review</title><author>Caster, W.O. ; Wang, Marian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-354d9f582f1d64c55782cc90a7fcdbb2086b29d85a4267b2594f48e7c29e29733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Aluminum - adverse effects</topic><topic>Aluminum - physiology</topic><topic>Alzheimer Disease - etiology</topic><topic>Animals</topic><topic>Brain Diseases - etiology</topic><topic>Dementia - etiology</topic><topic>Diet - adverse effects</topic><topic>Humans</topic><topic>Renal Dialysis - adverse effects</topic><topic>Uremia - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Caster, W.O.</creatorcontrib><creatorcontrib>Wang, Marian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Pollution Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>The Science of the total environment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Caster, W.O.</au><au>Wang, Marian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dietary aluminum and Alzheimer's disease — A review</atitle><jtitle>The Science of the total environment</jtitle><addtitle>Sci Total Environ</addtitle><date>1981</date><risdate>1981</risdate><volume>17</volume><issue>1</issue><spage>31</spage><epage>36</epage><pages>31-36</pages><issn>0048-9697</issn><eissn>1879-1026</eissn><abstract>Current evidence suggests that dietary aluminum is neither an essential nutrient nor a toxic element causing neurological damage. The phosphate and fluoride salts of aluminum are very insoluble. When fed in excess, aluminum increases the dietary needs for these anions. Aluminum hydroxide is used as an antacid that can prevent the phosphatemia seen in severe kidney damage. In Alzheimer's disease there is progressive decrease in brain mass with the accumulation of phospholipid-rich cell debris. These membrane tangles tend to accumulate aluminum and are easily stainable with silver.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>7010599</pmid><doi>10.1016/0048-9697(81)90105-4</doi><tpages>6</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0048-9697 |
ispartof | The Science of the total environment, 1981, Vol.17 (1), p.31-36 |
issn | 0048-9697 1879-1026 |
language | eng |
recordid | cdi_proquest_miscellaneous_15270706 |
source | MEDLINE; Access via ScienceDirect (Elsevier) |
subjects | Aluminum - adverse effects Aluminum - physiology Alzheimer Disease - etiology Animals Brain Diseases - etiology Dementia - etiology Diet - adverse effects Humans Renal Dialysis - adverse effects Uremia - metabolism |
title | Dietary aluminum and Alzheimer's disease — A review |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T14%3A36%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dietary%20aluminum%20and%20Alzheimer's%20disease%20%E2%80%94%20A%20review&rft.jtitle=The%20Science%20of%20the%20total%20environment&rft.au=Caster,%20W.O.&rft.date=1981&rft.volume=17&rft.issue=1&rft.spage=31&rft.epage=36&rft.pages=31-36&rft.issn=0048-9697&rft.eissn=1879-1026&rft_id=info:doi/10.1016/0048-9697(81)90105-4&rft_dat=%3Cproquest_cross%3E15270706%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15270706&rft_id=info:pmid/7010599&rft_els_id=0048969781901054&rfr_iscdi=true |