Translocation of zinc may contribute to seizure-induced death of neurons

Rats were subjected to seizures induced by kainic acid, and the resulting changes in CNS zinc staining were studied with the toluene sulfonamide quinoline fluorescence method. Seizures caused a loss of zinc staining from presynaptic boutons in many limbic and cerebrocortical regions. Simultaneously,...

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Veröffentlicht in:	Brain research 1989-02, Vol.480 (1), p.317-321
Hauptverfasser:	Frederickson, C.J., Hernandez, M.D., McGinty, J.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala - drug effects Amygdala - metabolism Amygdala - physiopathology Animals Biological and medical sciences Bouton Cell Survival Cerebellum - metabolism Endotoxin Epilepsy Hippocampus - drug effects Hippocampus - metabolism Hippocampus - physiopathology In Vitro Techniques Kainic Acid Limbic system Medical sciences Nerve Degeneration Nervous system involvement in other diseases. Miscellaneous Neurology Neuron death Neurotoxin Quinolines Rats Seizure Seizures - chemically induced Seizures - metabolism Seizures - physiopathology Sulfonamides Toluene Zinc Zinc - metabolism
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