From laparoscopic to open Kasai portoenterostomy: the outcome after reintroduction of open Kasai portoenterostomy in infant with biliary atresia

Purpose Apparently superior result was observed after open Kasai portoenterostomy in infant with biliary atresia. Our institute stopped performing laparoscopic portoenterostomy since 2007. We aimed to investigate the outcome after reintroduction of open portoenterostomy. Methods 27 non-syndromic inf...

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Veröffentlicht in:Pediatric surgery international 2014-06, Vol.30 (6), p.605-608
Hauptverfasser: Chan, Kin Wai E., Lee, Kim Hung, Wong, Hei Yi V., Tsui, Siu Yan B., Wong, Yuen Shan, Pang, Kit Yi K., Mou, Jennifer Wai Cheung, Tam, Yuk Him
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container_end_page 608
container_issue 6
container_start_page 605
container_title Pediatric surgery international
container_volume 30
creator Chan, Kin Wai E.
Lee, Kim Hung
Wong, Hei Yi V.
Tsui, Siu Yan B.
Wong, Yuen Shan
Pang, Kit Yi K.
Mou, Jennifer Wai Cheung
Tam, Yuk Him
description Purpose Apparently superior result was observed after open Kasai portoenterostomy in infant with biliary atresia. Our institute stopped performing laparoscopic portoenterostomy since 2007. We aimed to investigate the outcome after reintroduction of open portoenterostomy. Methods 27 non-syndromic infants underwent open Kasai portoenterostomy from 2007 to 2012. The age and the sex of the patient, the bilirubin level before the operation, the early clearance of jaundice (total bilirubin
doi_str_mv 10.1007/s00383-014-3499-5
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Our institute stopped performing laparoscopic portoenterostomy since 2007. We aimed to investigate the outcome after reintroduction of open portoenterostomy. Methods 27 non-syndromic infants underwent open Kasai portoenterostomy from 2007 to 2012. The age and the sex of the patient, the bilirubin level before the operation, the early clearance of jaundice (total bilirubin &lt;20 μmol/L within 6 month of portoenterostomy), the native liver survival at 2 years after the operation were reviewed. The results were retrospectively compared with all 16 infants who underwent laparoscopic Kasai portoenterostomy before 2007. Results All infants had type III biliary atresia. No statistical difference was observed regarding the age at operation and the pre-operative bilirubin level. The early clearance of jaundice rate was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation ( p  = 0.03). At 2 years after the operation, the native liver survival was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation ( p  = 0.03). Conclusion Reintroduction of open Kasai portoenterostomy was associated with superior early clearance of jaundice rate and 2-year native liver survival rate.</description><identifier>ISSN: 0179-0358</identifier><identifier>EISSN: 1437-9813</identifier><identifier>DOI: 10.1007/s00383-014-3499-5</identifier><identifier>PMID: 24722760</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Biliary Atresia - surgery ; Bilirubin - analysis ; Biomarkers - analysis ; Female ; Humans ; Infant ; Laparoscopy - methods ; Male ; Medicine ; Medicine &amp; Public Health ; Original Article ; Pediatric Surgery ; Pediatrics ; Portoenterostomy, Hepatic - methods ; Surgery ; Survival Rate ; Treatment Outcome</subject><ispartof>Pediatric surgery international, 2014-06, Vol.30 (6), p.605-608</ispartof><rights>Springer-Verlag Berlin Heidelberg 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-a4995abb85f0efd190a04bf479320c18fe9e5726c9684d0369c4cfaf7a36e4323</citedby><cites>FETCH-LOGICAL-c372t-a4995abb85f0efd190a04bf479320c18fe9e5726c9684d0369c4cfaf7a36e4323</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00383-014-3499-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00383-014-3499-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24722760$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan, Kin Wai E.</creatorcontrib><creatorcontrib>Lee, Kim Hung</creatorcontrib><creatorcontrib>Wong, Hei Yi V.</creatorcontrib><creatorcontrib>Tsui, Siu Yan B.</creatorcontrib><creatorcontrib>Wong, Yuen Shan</creatorcontrib><creatorcontrib>Pang, Kit Yi K.</creatorcontrib><creatorcontrib>Mou, Jennifer Wai Cheung</creatorcontrib><creatorcontrib>Tam, Yuk Him</creatorcontrib><title>From laparoscopic to open Kasai portoenterostomy: the outcome after reintroduction of open Kasai portoenterostomy in infant with biliary atresia</title><title>Pediatric surgery international</title><addtitle>Pediatr Surg Int</addtitle><addtitle>Pediatr Surg Int</addtitle><description>Purpose Apparently superior result was observed after open Kasai portoenterostomy in infant with biliary atresia. Our institute stopped performing laparoscopic portoenterostomy since 2007. We aimed to investigate the outcome after reintroduction of open portoenterostomy. Methods 27 non-syndromic infants underwent open Kasai portoenterostomy from 2007 to 2012. The age and the sex of the patient, the bilirubin level before the operation, the early clearance of jaundice (total bilirubin &lt;20 μmol/L within 6 month of portoenterostomy), the native liver survival at 2 years after the operation were reviewed. The results were retrospectively compared with all 16 infants who underwent laparoscopic Kasai portoenterostomy before 2007. Results All infants had type III biliary atresia. No statistical difference was observed regarding the age at operation and the pre-operative bilirubin level. The early clearance of jaundice rate was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation ( p  = 0.03). At 2 years after the operation, the native liver survival was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation ( p  = 0.03). Conclusion Reintroduction of open Kasai portoenterostomy was associated with superior early clearance of jaundice rate and 2-year native liver survival rate.</description><subject>Biliary Atresia - surgery</subject><subject>Bilirubin - analysis</subject><subject>Biomarkers - analysis</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Laparoscopy - methods</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Original Article</subject><subject>Pediatric Surgery</subject><subject>Pediatrics</subject><subject>Portoenterostomy, Hepatic - methods</subject><subject>Surgery</subject><subject>Survival Rate</subject><subject>Treatment Outcome</subject><issn>0179-0358</issn><issn>1437-9813</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kU9rFTEUxYMo9ln9AG4k4Kab0Zt_kxl3UmwVC93Udcjk3diUmWRMMki_hR_ZPF4VERQuZHF-99wcDiEvGbxhAPptARCD6IDJTshx7NQjsmNS6G4cmHhMdsD02IFQwwl5VsodAAyiH5-SEy4157qHHflxkdNCZ7vanIpLa3C0JppWjPSzLTbQNeWaMFZsek3L_Ttab5Gmrbq0ILW-CTRjiDWn_eZqSJEm_z8DGmIbb2Ol30O9pVOYg8331NaMJdjn5Im3c8EXD-8p-XLx4eb8Y3d1ffnp_P1V54TmtbMtr7LTNCgP6PdsBAty8lKPgoNjg8cRlea9G_tB7qHFdtJ567UVPUrBxSk5O_quOX3bsFSzhOJwnm3EtBXDFO8Z7wd1QF__hd6lLcf2uwOluOy5YI1iR8q1oCWjN2sOS0tmGJhDXeZYl2l1mUNdRrWdVw_O27Tg_vfGr34awI9AaVL8ivmP0_90_Qk8e6MV</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Chan, Kin Wai E.</creator><creator>Lee, Kim Hung</creator><creator>Wong, Hei Yi V.</creator><creator>Tsui, Siu Yan B.</creator><creator>Wong, Yuen Shan</creator><creator>Pang, Kit Yi K.</creator><creator>Mou, Jennifer Wai Cheung</creator><creator>Tam, Yuk Him</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20140601</creationdate><title>From laparoscopic to open Kasai portoenterostomy: the outcome after reintroduction of open Kasai portoenterostomy in infant with biliary atresia</title><author>Chan, Kin Wai E. ; 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Our institute stopped performing laparoscopic portoenterostomy since 2007. We aimed to investigate the outcome after reintroduction of open portoenterostomy. Methods 27 non-syndromic infants underwent open Kasai portoenterostomy from 2007 to 2012. The age and the sex of the patient, the bilirubin level before the operation, the early clearance of jaundice (total bilirubin &lt;20 μmol/L within 6 month of portoenterostomy), the native liver survival at 2 years after the operation were reviewed. The results were retrospectively compared with all 16 infants who underwent laparoscopic Kasai portoenterostomy before 2007. Results All infants had type III biliary atresia. No statistical difference was observed regarding the age at operation and the pre-operative bilirubin level. The early clearance of jaundice rate was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation ( p  = 0.03). At 2 years after the operation, the native liver survival was 81 % (22/27) after open operation and was 50 % (8/16) after laparoscopic operation ( p  = 0.03). Conclusion Reintroduction of open Kasai portoenterostomy was associated with superior early clearance of jaundice rate and 2-year native liver survival rate.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>24722760</pmid><doi>10.1007/s00383-014-3499-5</doi><tpages>4</tpages></addata></record>
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subjects Biliary Atresia - surgery
Bilirubin - analysis
Biomarkers - analysis
Female
Humans
Infant
Laparoscopy - methods
Male
Medicine
Medicine & Public Health
Original Article
Pediatric Surgery
Pediatrics
Portoenterostomy, Hepatic - methods
Surgery
Survival Rate
Treatment Outcome
title From laparoscopic to open Kasai portoenterostomy: the outcome after reintroduction of open Kasai portoenterostomy in infant with biliary atresia
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