Molecular mechanisms of lymphocyte extravasation. III. The loss of lymphocyte extravasation potential induced by pertussis toxin is not mediated via the activation of protein kinase C

The present study evaluated whether protein kinase C (PKC) activation was involved in the lymphocytosis promoting properties of pertussis toxin (Ptx). The exposure of mouse lymphocytes to phorbol esters (as a means to selectively activate PKC) caused a depression in their subsequent capacity to loca...

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Veröffentlicht in:	The Journal of immunology (1950) 1989-07, Vol.143 (1), p.229-238
Hauptverfasser:	Huang, K, Im, SY, Samlowski, WE, Daynes, RA
Format:	Artikel
Sprache:	eng
Schlagworte:	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Animals Antigens, Surface - analysis Bordetella pertussis Cell Adhesion - drug effects Cell Adhesion Molecules Cell Movement - drug effects Dermatitis, Contact - etiology Dinitrofluorobenzene - pharmacology Endothelium, Lymphatic - physiology Enzyme Activation Immunization, Passive Intestines Isoquinolines - pharmacology Lymph Nodes Lymphocytes - drug effects Lymphocytes - enzymology Lymphocytes - physiology Mice Mice, Inbred C3H Pertussis Toxin Piperazines - pharmacology Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Tetradecanoylphorbol Acetate - pharmacology Virulence Factors, Bordetella - pharmacology
Online-Zugang:	Volltext
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