TLR2 engagement on CD4 super(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis

We have previously demonstrated that mycobacterial lipoproteins engage TLR2 on human CD4 super(+) T cells and upregulate TCR-triggered IFN-[gamma] secretion and cell proliferation in vitro. Here we examined the role of CD4 super(+) T-cell-expressed TLR2 in Mycobacterium tuberculosis (MTB) Ag-specifi...

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Veröffentlicht in:	European journal of immunology 2014-05, Vol.44 (5), p.1410-1421
Hauptverfasser:	Reba, Scott M, Li, Qing, Onwuzulike, Sophia, Ding, Xuedong, Karim, Ahmad F, Hernandez, Yeritza, Fulton, Scott A, Harding, Clifford V, Lancioni, Christina L, Nagy, Nancy, Rodriguez, Myriam E, Wearsch, Pamela A, Rojas, Roxana E
Format:	Artikel
Sprache:	eng
Schlagworte:	Mycobacterium tuberculosis
Online-Zugang:	Volltext
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