Inducible Deletion of CD28 Prior to Secondary Nippostrongylus brasiliensis Infection Impairs Worm Expulsion and Recall of Protective Memory CD4+ T Cell Responses: e1003906

IL-13 driven Th2 immunity is indispensable for host protection against infection with the gastrointestinal nematode Nippostronglus brasiliensis. Disruption of CD28 mediated costimulation impairs development of adequate Th2 immunity, showing an importance for CD28 during the initiation of an immune r...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PLoS pathogens 2014-02, Vol.10 (2)
Hauptverfasser:	Ndlovu, Hlumani, Darby, Mathew, Froelich, Monika, Horsnell, William, Lühder, Fred, Hünig, Thomas, Brombacher, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Experiments Immune system Lymphocytes Recruitment Rodents T cell receptors Viral infections
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!