CRISPR-Cas systems for editing, regulating and targeting genomes

Targeted genome editing using engineered nucleases has rapidly gone from being a niche technology to a mainstream method used by many biological researchers. This widespread adoption has been largely fueled by the emergence of the clustered, regularly interspaced, short palindromic repeat (CRISPR) t...

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Veröffentlicht in:	Nature biotechnology 2014-04, Vol.32 (4), p.347-355
Hauptverfasser:	Sander, Jeffry D, Joung, J Keith
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/1511 631/1647/1513 631/61 Agriculture Animals Bioinformatics Biological research Biomedical Engineering/Biotechnology Biomedicine Biotechnology Clustered Regularly Interspaced Short Palindromic Repeats CRISPR CRISPR-Cas Systems Forecasts and trends Gene expression Gene loci Gene targeting Genetic engineering Genetic Engineering - methods Genetic screening Genomes Genomics - methods Humans Life Sciences Medical research Mice Mutation Organisms Proteins Rabbits Rats review-article Yeast
Online-Zugang:	Volltext
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