$Relaxant effect of 1-butanol fraction from Elaeagnus pungens leaf through inhibiting l-type Ca2+ channel on guinea pig tracheal smooth muscle$

Relaxant effect of 1-butanol fraction from Elaeagnus pungens leaf through inhibiting l-type Ca2+ channel on guinea pig tracheal smooth muscle

The leaf of Elaeagnus pungens thunb. (Family Elaeagnaceae) has been documented as an effective herb for the treatment of asthma and chronic bronchitis in traditional Chinese medicine. In the past years, only a few of preliminary studies reported the chemical constituents and pharmacology effects of...

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Veröffentlicht in:	Journal of ethnopharmacology 2013-10, Vol.150 (1), p.196-201
Hauptverfasser:	Ge, Yue-bin, Dai, Qian, Wan, Ding-rong, Liu, Qing-hua, Mei, Zhi-nan
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Butanol - chemistry 1-butanol fraction 4-aminopyridine acetylcholine Animals antagonists asthma bronchi Bronchi - cytology bronchitis Ca2+ channels calcium Calcium - metabolism Calcium Channels, L-Type - physiology Cells, Cultured cyclic GMP Elaeagnaceae Elaeagnus Elaeagnus pungens Elaeagnus pungens leaf fluorescence glibenclamide Guinea pig tracheal smooth muscle Guinea Pigs histamine In Vitro Techniques indomethacin leaves Male Muscle Contraction - drug effects Muscle, Smooth - drug effects Muscle, Smooth - physiology myocytes Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism nitric oxide nitric oxide synthase Oriental traditional medicine Plant Extracts - pharmacology Plant Leaves potassium propranolol prostaglandin synthase Relaxation smooth muscle Solvents - chemistry Trachea - drug effects Trachea - physiology
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