Parent-of-Origin Effects Implicate Epigenetic Regulation of Experimental Autoimmune Encephalomyelitis and Identify Imprinted Dlk1 as a Novel Risk Gene: e1004265

Parent-of-origin effects comprise a range of genetic and epigenetic mechanisms of inheritance. Recently, detection of such effects implicated epigenetic mechanisms in the etiology of multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system. We here sought to dissect the...

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Veröffentlicht in:	PLoS genetics 2014-03, Vol.10 (3)
Hauptverfasser:	Stridh, Pernilla, Ruhrmann, Sabrina, Bergman, Petra, Hedreul, Mélanie Thessén, Flytzani, Sevasti, Beyeen, Amennai Daniel, Gillett, Alan, Krivosija, Nina, Öckinger, Johan, Ferguson-Smith, Anne C, Jagodic, Maja
Format:	Artikel
Sprache:	eng
Schlagworte:	Deoxyribonucleic acid Disease DNA DNA methylation Epigenetics Gene expression Multiple sclerosis Nervous system Pathogenesis
Online-Zugang:	Volltext
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