Rabies virus-like particles expressed in HEK293 cells

Abstract Rabies is an infectious viral disease with a mortality rate close to 100%. Currently, there is a need to generate cheaper and more immunogenic vaccines for the effective prevention of rabies, mostly in developing countries. Virus-like particles have been widely used in viral vaccine product...

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Veröffentlicht in:	Vaccine 2014-05, Vol.32 (24), p.2799-2804
Hauptverfasser:	Fontana, Diego, Kratje, Ricardo, Etcheverrigaray, Marina, Prieto, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Antibodies, Viral - blood Antigens, Viral - immunology Applied microbiology Biological and medical sciences Cloning Developing countries Female Fluorescence microscopy Fundamental and applied biological sciences. Psychology Genetic Vectors Glycoproteins - immunology HEK293 Cells Humans Immune response Immunity, Humoral Immunization Immunogenicity Industrialized nations LDCs Mice Mice, Inbred BALB C Microbiology Miscellaneous Plasmids Proteins Rabies Rabies Vaccines - immunology Rabies virus Rabies virus - growth & development RNA polymerase Transduction, Genetic Vaccine Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Virus-Like Particle - immunology Viral diseases Viral Envelope Proteins - immunology Virology Virus Cultivation Virus-like particles Viruses
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