Impaired expression of CD26 compromises T‐cell recruitment in human visceral leishmaniasis

An inefficient Th1 response, coupled with skewed Th2 cytokine production, has been implicated to increase susceptibility to visceral leishmaniasis (VL) infection. The expression of the dipeptidyl peptidase Cd26 by polarized Th1 activates a chemokine cascade that recruits Th1 recruitment to the patho...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of immunology 2012-10, Vol.42 (10), p.2782-2791
Hauptverfasser:	Rai, Ambak K., Thakur, Chandreshwar P., Kumar, Prabin, Mitra, Dipendra K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibodies, Blocking - pharmacology CD26 Cell Movement Cells, Cultured Child Child, Preschool Cytokines - immunology Dipeptidyl Peptidase 4 - genetics Dipeptidyl Peptidase 4 - metabolism Down-Regulation Female Humans Immunologic Memory Immunosuppression Leishmaniasis, Visceral - immunology Male Middle Aged Mycobacterium T cell recruitment Th1 Cells - drug effects Th1 Cells - immunology Th1-Th2 Balance Th2 Cells - drug effects Th2 Cells - immunology Visceral leishmaniasis Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!