CD46: The ‘multitasker’ of complement proteins

Complement is undeniably quintessential for innate immunity by detecting and eliminating infectious microorganisms. Recent work, however, highlights an equally profound impact of complement on the induction and regulation of a wide range of immune cells. In particular, the complement regulator CD46...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2013-12, Vol.45 (12), p.2808-2820
Hauptverfasser:	Yamamoto, Hidekazu, Fara, Antonella Francesca, Dasgupta, Prokar, Kemper, Claudia
Format:	Artikel
Sprache:	eng
Schlagworte:	adaptive immunity Autoimmunity Biochemistry Biology CD4-positive T-lymphocytes CD46 Complement Complement System Proteins - immunology Control Humans Immunity Immunity, Innate Infection innate immunity Membrane Cofactor Protein - immunology microorganisms Modulation Modulators proteins Regulators Signal Transduction Th1 cells
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