Cigarette smoke causes inhibition of the immune response to intratracheally administered antigens

Chronic inhalation of cigarette smoke in rats preferentially inhibited the plaque-forming cell (PFC) response of lung-associated lymph nodes (LALN) to sheep red blood cells (SRBC), compared to anatomically distant lymph nodes. Inhibition of the antibody response in LALN of smoke-exposed animals was...

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Veröffentlicht in:	Toxicology and applied pharmacology 1989-03, Vol.97 (3), p.489-499
Hauptverfasser:	Sopori, Mohan L., Cherian, Susamma, Chilukuri, Ranga, Shopp, George M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Formation Antigens - administration & dosage Biological and medical sciences Lung - immunology Lymph Nodes - immunology Lymphocyte Activation Lymphoid Tissue - immunology Macrophages - physiology Medical sciences Nicotiana Plants, Toxic Rats Rats, Inbred Strains Smoke - adverse effects Tobacco, tobacco smoking Toxicology
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