Angiogenic factor thymidine phosphorylase associates with angiogenesis and lymphangiogenesis in the intestinal-type gastric cancer

As an angiogenic factor, thymidine phosphorylase (TP) expression in primary tumours has been thought to be a risk factor for lymph node (LN) and hepaticmetastasis in patients with gastric adenocarcinoma. However, the molecular basis for the induction of metastasis by TP is largely unknown. We aim to...

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Veröffentlicht in:	Pathology 2014-06, Vol.46 (4), p.316-324
Hauptverfasser:	Zhang, Xianglan, Zheng, Zhenlong, Shin, You Keun, Kim, Ki-Yeol, Rha, Sun Young, Noh, Sung Hoon, Chung, Hyun Cheol, Jeung, Hei-Cheul
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - enzymology Adenocarcinoma - mortality Adenocarcinoma - pathology Adult Aged Angiogenesis Animals Blotting, Western Female gastric cancer Heterografts Humans Immunohistochemistry Kaplan-Meier Estimate lymphangiogenesis Lymphangiogenesis - physiology Male Mice Mice, Nude Middle Aged Neovascularization, Pathologic - enzymology Prognosis Stomach Neoplasms - enzymology Stomach Neoplasms - mortality Stomach Neoplasms - pathology thymidine phosphorylase Thymidine Phosphorylase - metabolism
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