The effect of recombinant human fibroblast growth factor-18 on articular cartilage following single impact load

ABSTRACT The aim of this in vitro study was to ascertain the effect of recombinant human Fibroblast Growth Factor‐18 (rhFGF18) on the repair response of mechanically damaged articular cartilage. Articular cartilage discs were harvested from healthy mature horses (n = 4) and subjected to single impac...

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Veröffentlicht in:	Journal of orthopaedic research 2014-07, Vol.32 (7), p.923-927
Hauptverfasser:	Barr, Lynne, Getgood, Alan, Guehring, Hans, Rushton, Neil, Henson, Frances M. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggrecans - metabolism Animals Apoptosis cartilage Cartilage, Articular - drug effects Cartilage, Articular - injuries Cartilage, Articular - metabolism Cell Death Collagen Type II - metabolism Culture Media - chemistry Epitopes - metabolism FGF18 Fibroblast Growth Factors - pharmacology Glycosaminoglycans - metabolism Horses Humans load Recombinant Proteins - pharmacology Stress, Mechanical Time Factors Wound Healing - drug effects
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