Pancreaticoduodenectomy: Outcomes in a Low-Volume, Specialised Hepato Pancreato Biliary Unit

Background This study was designed to evaluate the outcomes of pancreaticoduodenectomy (PD) at a low-volume specialised Hepato Pancreato Biliary (HPB) unit. Volume outcome analyses show significantly better results for patients undergoing PD at high-volume centres (Begg et al. JAMA 280:1747–1751, 19...

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Veröffentlicht in:World journal of surgery 2014-06, Vol.38 (6), p.1484-1490
Hauptverfasser: Kanhere, H. A., Trochsler, M. I., Kanhere, M. H., Lord, A. N., Maddern, G. J.
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container_end_page 1490
container_issue 6
container_start_page 1484
container_title World journal of surgery
container_volume 38
creator Kanhere, H. A.
Trochsler, M. I.
Kanhere, M. H.
Lord, A. N.
Maddern, G. J.
description Background This study was designed to evaluate the outcomes of pancreaticoduodenectomy (PD) at a low-volume specialised Hepato Pancreato Biliary (HPB) unit. Volume outcome analyses show significantly better results for patients undergoing PD at high-volume centres (Begg et al. JAMA 280:1747–1751, 1998 ; Finlayson et al. Arch Surg 138:721–725, 2003 ; Birkmeyer et al. N Engl J Med 346:1128–1137, 2002 ; Gouma et al. Ann Surg 232:786–795, 2000 ). Centralisation of PD seems to be the logical conclusion to be drawn from these results. In countries like Australia with a small and widely dispersed population, centralisation may not be always feasible. Alternative strategy would be to have similar systems in place to those in high-volume centres to achieve similar results at low-volume centres. Many Australian tertiary care centres perform low to medium volumes of PD (Chen et al. HPB 12:101–108, 2010 ; Kwok et al. ANZ J Surg 80:605–608, 2010 ; Barnett and Collier ANZ J Surg 76:563–568, 2006 ; Samra et al. Hepatobiliary Pancreat Dis Int 10:415–421, 2011 ). Most of these have a specialised HPB unit, accredited by the Australia and New Zealand Hepatic pancreatic and biliary association (ANZHPBA), as training units for post fellowship training in HPB surgery. It is imperative to perform outcome-based analyses in these units to ensure safety and high quality of care. Methods Retrospective analysis of database for periampullary carcinoma (1998 till date) was performed in an ANZHPBA accredited HPB unit based at a tertiary care teaching hospital in South Australia. Because age older than 74 years is shown to be a predictive marker of increased morbidity and mortality after a PD, we analysed the outcomes in this subset of patients separately. Results Fifty-three patients underwent PD in 14 years. Overall mortality was 3.8 %. The last in hospital mortality was in 1999. The morbidity rates and the oncologic outcomes were similar to those in high-volume units. Conclusions PD can be safely performed in a low-volume specialised unit at centres where the amenities and processes at high-volume centres can be replicated.
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A. ; Trochsler, M. I. ; Kanhere, M. H. ; Lord, A. N. ; Maddern, G. J.</creator><creatorcontrib>Kanhere, H. A. ; Trochsler, M. I. ; Kanhere, M. H. ; Lord, A. N. ; Maddern, G. J.</creatorcontrib><description>Background This study was designed to evaluate the outcomes of pancreaticoduodenectomy (PD) at a low-volume specialised Hepato Pancreato Biliary (HPB) unit. Volume outcome analyses show significantly better results for patients undergoing PD at high-volume centres (Begg et al. JAMA 280:1747–1751, 1998 ; Finlayson et al. Arch Surg 138:721–725, 2003 ; Birkmeyer et al. N Engl J Med 346:1128–1137, 2002 ; Gouma et al. Ann Surg 232:786–795, 2000 ). Centralisation of PD seems to be the logical conclusion to be drawn from these results. In countries like Australia with a small and widely dispersed population, centralisation may not be always feasible. Alternative strategy would be to have similar systems in place to those in high-volume centres to achieve similar results at low-volume centres. Many Australian tertiary care centres perform low to medium volumes of PD (Chen et al. HPB 12:101–108, 2010 ; Kwok et al. ANZ J Surg 80:605–608, 2010 ; Barnett and Collier ANZ J Surg 76:563–568, 2006 ; Samra et al. Hepatobiliary Pancreat Dis Int 10:415–421, 2011 ). Most of these have a specialised HPB unit, accredited by the Australia and New Zealand Hepatic pancreatic and biliary association (ANZHPBA), as training units for post fellowship training in HPB surgery. It is imperative to perform outcome-based analyses in these units to ensure safety and high quality of care. Methods Retrospective analysis of database for periampullary carcinoma (1998 till date) was performed in an ANZHPBA accredited HPB unit based at a tertiary care teaching hospital in South Australia. Because age older than 74 years is shown to be a predictive marker of increased morbidity and mortality after a PD, we analysed the outcomes in this subset of patients separately. Results Fifty-three patients underwent PD in 14 years. Overall mortality was 3.8 %. The last in hospital mortality was in 1999. The morbidity rates and the oncologic outcomes were similar to those in high-volume units. Conclusions PD can be safely performed in a low-volume specialised unit at centres where the amenities and processes at high-volume centres can be replicated.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/s00268-013-2431-9</identifier><identifier>PMID: 24378551</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Abdominal Surgery ; Age Factors ; Aged ; Animals ; Australia ; Cardiac Surgery ; Cohort Studies ; Complex Surgery ; Female ; Follow-Up Studies ; General Surgery ; Hospital Mortality ; Humans ; Intraductal Papillary Mucinous Tumour ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; National Surgical Quality Improvement Program ; Pancreatic Fistula ; Pancreatic Neoplasms - mortality ; Pancreatic Neoplasms - pathology ; Pancreatic Neoplasms - surgery ; Pancreaticoduodenectomy - adverse effects ; Pancreaticoduodenectomy - methods ; Pancreaticoduodenectomy - mortality ; Postoperative Complications - mortality ; Postoperative Complications - physiopathology ; Retrospective Studies ; Risk Assessment ; Sex Factors ; Surgery ; Surgery Department, Hospital - statistics &amp; numerical data ; Surgical Expertise ; Thoracic Surgery ; Time Factors ; Treatment Outcome ; Vascular Surgery ; Workload</subject><ispartof>World journal of surgery, 2014-06, Vol.38 (6), p.1484-1490</ispartof><rights>Société Internationale de Chirurgie 2013</rights><rights>2014 The Author(s) under exclusive licence to Société Internationale de Chirurgie</rights><rights>Société Internationale de Chirurgie 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4653-9ff4b66f819286b84712be0c377ee2530b98df455d7d8e86bd1832a87de655d93</citedby><cites>FETCH-LOGICAL-c4653-9ff4b66f819286b84712be0c377ee2530b98df455d7d8e86bd1832a87de655d93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00268-013-2431-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00268-013-2431-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,41488,42557,45574,45575,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24378551$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kanhere, H. A.</creatorcontrib><creatorcontrib>Trochsler, M. I.</creatorcontrib><creatorcontrib>Kanhere, M. H.</creatorcontrib><creatorcontrib>Lord, A. N.</creatorcontrib><creatorcontrib>Maddern, G. J.</creatorcontrib><title>Pancreaticoduodenectomy: Outcomes in a Low-Volume, Specialised Hepato Pancreato Biliary Unit</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><addtitle>World J Surg</addtitle><description>Background This study was designed to evaluate the outcomes of pancreaticoduodenectomy (PD) at a low-volume specialised Hepato Pancreato Biliary (HPB) unit. Volume outcome analyses show significantly better results for patients undergoing PD at high-volume centres (Begg et al. JAMA 280:1747–1751, 1998 ; Finlayson et al. Arch Surg 138:721–725, 2003 ; Birkmeyer et al. N Engl J Med 346:1128–1137, 2002 ; Gouma et al. Ann Surg 232:786–795, 2000 ). Centralisation of PD seems to be the logical conclusion to be drawn from these results. In countries like Australia with a small and widely dispersed population, centralisation may not be always feasible. Alternative strategy would be to have similar systems in place to those in high-volume centres to achieve similar results at low-volume centres. Many Australian tertiary care centres perform low to medium volumes of PD (Chen et al. HPB 12:101–108, 2010 ; Kwok et al. ANZ J Surg 80:605–608, 2010 ; Barnett and Collier ANZ J Surg 76:563–568, 2006 ; Samra et al. Hepatobiliary Pancreat Dis Int 10:415–421, 2011 ). Most of these have a specialised HPB unit, accredited by the Australia and New Zealand Hepatic pancreatic and biliary association (ANZHPBA), as training units for post fellowship training in HPB surgery. It is imperative to perform outcome-based analyses in these units to ensure safety and high quality of care. Methods Retrospective analysis of database for periampullary carcinoma (1998 till date) was performed in an ANZHPBA accredited HPB unit based at a tertiary care teaching hospital in South Australia. Because age older than 74 years is shown to be a predictive marker of increased morbidity and mortality after a PD, we analysed the outcomes in this subset of patients separately. Results Fifty-three patients underwent PD in 14 years. Overall mortality was 3.8 %. The last in hospital mortality was in 1999. The morbidity rates and the oncologic outcomes were similar to those in high-volume units. 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A.</au><au>Trochsler, M. I.</au><au>Kanhere, M. H.</au><au>Lord, A. N.</au><au>Maddern, G. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pancreaticoduodenectomy: Outcomes in a Low-Volume, Specialised Hepato Pancreato Biliary Unit</atitle><jtitle>World journal of surgery</jtitle><stitle>World J Surg</stitle><addtitle>World J Surg</addtitle><date>2014-06</date><risdate>2014</risdate><volume>38</volume><issue>6</issue><spage>1484</spage><epage>1490</epage><pages>1484-1490</pages><issn>0364-2313</issn><eissn>1432-2323</eissn><abstract>Background This study was designed to evaluate the outcomes of pancreaticoduodenectomy (PD) at a low-volume specialised Hepato Pancreato Biliary (HPB) unit. Volume outcome analyses show significantly better results for patients undergoing PD at high-volume centres (Begg et al. JAMA 280:1747–1751, 1998 ; Finlayson et al. Arch Surg 138:721–725, 2003 ; Birkmeyer et al. N Engl J Med 346:1128–1137, 2002 ; Gouma et al. Ann Surg 232:786–795, 2000 ). Centralisation of PD seems to be the logical conclusion to be drawn from these results. In countries like Australia with a small and widely dispersed population, centralisation may not be always feasible. Alternative strategy would be to have similar systems in place to those in high-volume centres to achieve similar results at low-volume centres. Many Australian tertiary care centres perform low to medium volumes of PD (Chen et al. HPB 12:101–108, 2010 ; Kwok et al. ANZ J Surg 80:605–608, 2010 ; Barnett and Collier ANZ J Surg 76:563–568, 2006 ; Samra et al. Hepatobiliary Pancreat Dis Int 10:415–421, 2011 ). Most of these have a specialised HPB unit, accredited by the Australia and New Zealand Hepatic pancreatic and biliary association (ANZHPBA), as training units for post fellowship training in HPB surgery. It is imperative to perform outcome-based analyses in these units to ensure safety and high quality of care. Methods Retrospective analysis of database for periampullary carcinoma (1998 till date) was performed in an ANZHPBA accredited HPB unit based at a tertiary care teaching hospital in South Australia. Because age older than 74 years is shown to be a predictive marker of increased morbidity and mortality after a PD, we analysed the outcomes in this subset of patients separately. Results Fifty-three patients underwent PD in 14 years. Overall mortality was 3.8 %. The last in hospital mortality was in 1999. The morbidity rates and the oncologic outcomes were similar to those in high-volume units. Conclusions PD can be safely performed in a low-volume specialised unit at centres where the amenities and processes at high-volume centres can be replicated.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>24378551</pmid><doi>10.1007/s00268-013-2431-9</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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source Wiley Online Library - AutoHoldings Journals; MEDLINE; SpringerNature Journals
subjects Abdominal Surgery
Age Factors
Aged
Animals
Australia
Cardiac Surgery
Cohort Studies
Complex Surgery
Female
Follow-Up Studies
General Surgery
Hospital Mortality
Humans
Intraductal Papillary Mucinous Tumour
Male
Medicine
Medicine & Public Health
Middle Aged
National Surgical Quality Improvement Program
Pancreatic Fistula
Pancreatic Neoplasms - mortality
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - surgery
Pancreaticoduodenectomy - adverse effects
Pancreaticoduodenectomy - methods
Pancreaticoduodenectomy - mortality
Postoperative Complications - mortality
Postoperative Complications - physiopathology
Retrospective Studies
Risk Assessment
Sex Factors
Surgery
Surgery Department, Hospital - statistics & numerical data
Surgical Expertise
Thoracic Surgery
Time Factors
Treatment Outcome
Vascular Surgery
Workload
title Pancreaticoduodenectomy: Outcomes in a Low-Volume, Specialised Hepato Pancreato Biliary Unit
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