Mechanism of mouse skin tumor promotion by n-dodecane

Application of the alkane n-dodecane to the dorsal skin of 6–8 week old female SENCAR mice initiated with 10 nmol dimethylbenz[a]anthracene led to papilloma formation in the majority of treated animals. Compared to the potent phorbol diester 12-O-tetradecanoylphorbol-13-acetate (TPA), n-dodecane was...

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Veröffentlicht in:	Carcinogenesis (New York) 1987-12, Vol.8 (12), p.1787-1790
Hauptverfasser:	Baxter, C.Stuart, Miller, Marian L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetone Alkanes Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Chemical agents Cocarcinogenesis Diterpenes Female Medical sciences Mice Papilloma - chemically induced Skin Neoplasms - chemically induced Terpenes Tetradecanoylphorbol Acetate Tumors
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