Investigations into the biochemical effects of region-specific nephrotoxins

1H NMR spectroscopy provides a useful initial biochemical screen with which to detect abnormal patterns of metabolites in urine collected from animals with different sites of nephrotoxic lesions. Male Fischer 344 rats were treated with nephrotoxic doses of sodium chromate (pars convoluta of proximal...

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Veröffentlicht in:	Molecular pharmacology 1989-02, Vol.35 (2), p.242-250
Hauptverfasser:	GARTLAND, K. P. R, BONNER, F. W, NICHOLSON, J. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylglucosaminidase - urine Animals Aziridines - toxicity Biological and medical sciences Butadienes - toxicity Chromates - toxicity Cisplatin - toxicity Drug toxicity and drugs side effects treatment Ethylamines - toxicity Fatty Acids - metabolism Kidney - drug effects Kidney Medulla - drug effects Kidney Tubules - drug effects Magnetic Resonance Spectroscopy Male Medical sciences Mercuric Chloride - toxicity Pharmacology. Drug treatments Rats Rats, Inbred F344 Sodium Compounds Toxicity: urogenital system
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