Aberrant histone methylation and the effect of Suv39H1 siRNA on gastric carcinoma

The present study aimed to investigate the involvement of the Suv39H1 histone methyltransferase in the epigenetic changes in the euchromatic promoter in gastric carcinoma. We retrospectively analyzed the protein of Suv39H1 and tri-methylated histone H3 lysine 9 (H3K9) and histone H3 lysine 4 (H3K4)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncology reports 2014-06, Vol.31 (6), p.2593-2600
Hauptverfasser:	CAI, LISHENG, MA, XUDONG, HUANG, YIQUN, ZOU, YONG, CHEN, XINGSHENG
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apoptosis Apoptosis - genetics Body mass index Caspase 3 - biosynthesis Cell growth Cell Proliferation - genetics Chromatin Deoxyribonucleic acid Development and progression DNA DNA methylation DNA Methylation - genetics Epigenesis, Genetic Epigenetics Female Gastric cancer gastric carcinoma Gene expression Gene Expression Regulation, Neoplastic Genes Genetic aspects Health aspects histone methylation Histones - metabolism Humans Innovations Leukemia Male Metastasis Methyltransferases Methyltransferases - antagonists & inhibitors Methyltransferases - genetics Middle Aged Molecular targeted therapy Promoter Regions, Genetic Properties Protein expression Proteins Proto-Oncogene Proteins c-bcl-2 - biosynthesis Proto-Oncogene Proteins c-myc - biosynthesis Repressor Proteins - antagonists & inhibitors Repressor Proteins - genetics RNA, Small Interfering - genetics siRNA interference Stomach cancer Stomach Neoplasms - genetics Stomach Neoplasms - pathology Suv39H1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!