ERCC1 and BRCA1 mRNA expressions are associated with clinical outcome of non-small cell lung cancer treated with platinum-based chemotherapy

We conducted a perspective study to investigate whether the expression of excision repair cross-complementing 1 (ERCC1), xeroderma pigmentosum group G (XPG), breast cancer 1 (BRCA1), and ribonucleotide reductase M1 (RRM1) is correlated with clinical outcome of non-small cell lung cancer (NSCLC). Pat...

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Veröffentlicht in:	Tumor biology 2014-05, Vol.35 (5), p.4697-4704
Hauptverfasser:	Qin, Xiuguang, Yao, Wenjian, Li, Weiwei, Feng, Xianjun, Huo, Xiaoqing, Yang, Shujuan, Zhao, Hui, Gu, Xiaomeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomedical and Life Sciences Biomedicine BRCA1 Protein - genetics Cancer Research Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - mortality Chemotherapy Clinical outcomes DNA-Binding Proteins - genetics Endonucleases - genetics Female Gene expression Humans Lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - genetics Lung Neoplasms - mortality Male Middle Aged Nuclear Proteins - genetics Platinum Proportional Hazards Models Research Article Ribonucleic acid RNA RNA, Messenger - analysis Transcription Factors - genetics Treatment Outcome
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