High incidence of Dacron conduit stenosis for extracardiac Fontan procedure
Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no info...
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Veröffentlicht in: | The Journal of thoracic and cardiovascular surgery 2014-05, Vol.147 (5), p.1568-1572 |
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container_title | The Journal of thoracic and cardiovascular surgery |
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creator | van Brakel, Thomas J., MD, PhD Schoof, Paul H., MD, PhD de Roo, Frank, MPA Nikkels, Peter G.J., MD, PhD Evens, Fabiola C.M., MD Haas, Felix, MD |
description | Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit. |
doi_str_mv | 10.1016/j.jtcvs.2013.07.013 |
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Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.</description><identifier>ISSN: 0022-5223</identifier><identifier>EISSN: 1097-685X</identifier><identifier>DOI: 10.1016/j.jtcvs.2013.07.013</identifier><identifier>PMID: 23988293</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation - adverse effects ; Blood Vessel Prosthesis Implantation - instrumentation ; Cardiothoracic Surgery ; Child, Preschool ; Constriction, Pathologic ; Device Removal ; Fontan Procedure - adverse effects ; Graft Occlusion, Vascular - diagnosis ; Graft Occlusion, Vascular - epidemiology ; Graft Occlusion, Vascular - surgery ; Heart Defects, Congenital - physiopathology ; Heart Defects, Congenital - surgery ; Humans ; Incidence ; Length of Stay ; Netherlands - epidemiology ; Polyethylene Terephthalates ; Prosthesis Design ; Reoperation ; Retrospective Studies ; Time Factors ; Treatment Outcome</subject><ispartof>The Journal of thoracic and cardiovascular surgery, 2014-05, Vol.147 (5), p.1568-1572</ispartof><rights>The American Association for Thoracic Surgery</rights><rights>2014 The American Association for Thoracic Surgery</rights><rights>Copyright © 2014 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-66064029a1a52e2e3d024b17995e8f10e342e445efdc7d32733d7ea36a96e3173</citedby><cites>FETCH-LOGICAL-c525t-66064029a1a52e2e3d024b17995e8f10e342e445efdc7d32733d7ea36a96e3173</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jtcvs.2013.07.013$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23988293$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van Brakel, Thomas J., MD, PhD</creatorcontrib><creatorcontrib>Schoof, Paul H., MD, PhD</creatorcontrib><creatorcontrib>de Roo, Frank, MPA</creatorcontrib><creatorcontrib>Nikkels, Peter G.J., MD, PhD</creatorcontrib><creatorcontrib>Evens, Fabiola C.M., MD</creatorcontrib><creatorcontrib>Haas, Felix, MD</creatorcontrib><title>High incidence of Dacron conduit stenosis for extracardiac Fontan procedure</title><title>The Journal of thoracic and cardiovascular surgery</title><addtitle>J Thorac Cardiovasc Surg</addtitle><description>Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.</description><subject>Blood Vessel Prosthesis</subject><subject>Blood Vessel Prosthesis Implantation - adverse effects</subject><subject>Blood Vessel Prosthesis Implantation - instrumentation</subject><subject>Cardiothoracic Surgery</subject><subject>Child, Preschool</subject><subject>Constriction, Pathologic</subject><subject>Device Removal</subject><subject>Fontan Procedure - adverse effects</subject><subject>Graft Occlusion, Vascular - diagnosis</subject><subject>Graft Occlusion, Vascular - epidemiology</subject><subject>Graft Occlusion, Vascular - surgery</subject><subject>Heart Defects, Congenital - physiopathology</subject><subject>Heart Defects, Congenital - surgery</subject><subject>Humans</subject><subject>Incidence</subject><subject>Length of Stay</subject><subject>Netherlands - epidemiology</subject><subject>Polyethylene Terephthalates</subject><subject>Prosthesis Design</subject><subject>Reoperation</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0022-5223</issn><issn>1097-685X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFP3TAQhC1UBK_QX1Cp8rGXhLUdxy-HVqqgFFQkDoDUm2XsTes0z6Z2guDf1-FRDr1wmsvMjvYbQt4zqBmw9mioh8ne55oDEzWousgOWTHoVNWu5Y83ZAXAeSU5F_vkbc4DAChg3R7Z56Jbr3knVuT7mf_5i_pgvcNgkcaenhibYqA2Bjf7ieYJQ8w-0z4mig9TMtYk542lpzFMJtC7FC26OeEh2e3NmPHdsx6Qm9Ov18dn1cXlt_PjLxeVlVxOVdtC2wDvDDOSI0fhgDe3THWdxHXPAEXDsWkk9s4qJ7gSwik0ojVdi4IpcUA-bu-W5j8z5klvfLY4jiZgnLNmkjPRgORQrGJrLS_lnLDXd8lvTHrUDPRCUQ_6iaJeKGpQukhJfXgumG836F4y_7AVw6etAcub9x6TztYv_JxPaCfton-l4PN_eTv64K0Zf-Mj5iHOKRSCmunMNeirZchlRybKhKqR4i9SyJhf</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>van Brakel, Thomas J., MD, PhD</creator><creator>Schoof, Paul H., MD, PhD</creator><creator>de Roo, Frank, MPA</creator><creator>Nikkels, Peter G.J., MD, PhD</creator><creator>Evens, Fabiola C.M., MD</creator><creator>Haas, Felix, MD</creator><general>Mosby, Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140501</creationdate><title>High incidence of Dacron conduit stenosis for extracardiac Fontan procedure</title><author>van Brakel, Thomas J., MD, PhD ; Schoof, Paul H., MD, PhD ; de Roo, Frank, MPA ; Nikkels, Peter G.J., MD, PhD ; Evens, Fabiola C.M., MD ; Haas, Felix, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-66064029a1a52e2e3d024b17995e8f10e342e445efdc7d32733d7ea36a96e3173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Blood Vessel Prosthesis</topic><topic>Blood Vessel Prosthesis Implantation - adverse effects</topic><topic>Blood Vessel Prosthesis Implantation - instrumentation</topic><topic>Cardiothoracic Surgery</topic><topic>Child, Preschool</topic><topic>Constriction, Pathologic</topic><topic>Device Removal</topic><topic>Fontan Procedure - adverse effects</topic><topic>Graft Occlusion, Vascular - diagnosis</topic><topic>Graft Occlusion, Vascular - epidemiology</topic><topic>Graft Occlusion, Vascular - surgery</topic><topic>Heart Defects, Congenital - physiopathology</topic><topic>Heart Defects, Congenital - surgery</topic><topic>Humans</topic><topic>Incidence</topic><topic>Length of Stay</topic><topic>Netherlands - epidemiology</topic><topic>Polyethylene Terephthalates</topic><topic>Prosthesis Design</topic><topic>Reoperation</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van Brakel, Thomas J., MD, PhD</creatorcontrib><creatorcontrib>Schoof, Paul H., MD, PhD</creatorcontrib><creatorcontrib>de Roo, Frank, MPA</creatorcontrib><creatorcontrib>Nikkels, Peter G.J., MD, PhD</creatorcontrib><creatorcontrib>Evens, Fabiola C.M., MD</creatorcontrib><creatorcontrib>Haas, Felix, MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van Brakel, Thomas J., MD, PhD</au><au>Schoof, Paul H., MD, PhD</au><au>de Roo, Frank, MPA</au><au>Nikkels, Peter G.J., MD, PhD</au><au>Evens, Fabiola C.M., MD</au><au>Haas, Felix, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High incidence of Dacron conduit stenosis for extracardiac Fontan procedure</atitle><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle><addtitle>J Thorac Cardiovasc Surg</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>147</volume><issue>5</issue><spage>1568</spage><epage>1572</epage><pages>1568-1572</pages><issn>0022-5223</issn><eissn>1097-685X</eissn><abstract>Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>23988293</pmid><doi>10.1016/j.jtcvs.2013.07.013</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation - adverse effects Blood Vessel Prosthesis Implantation - instrumentation Cardiothoracic Surgery Child, Preschool Constriction, Pathologic Device Removal Fontan Procedure - adverse effects Graft Occlusion, Vascular - diagnosis Graft Occlusion, Vascular - epidemiology Graft Occlusion, Vascular - surgery Heart Defects, Congenital - physiopathology Heart Defects, Congenital - surgery Humans Incidence Length of Stay Netherlands - epidemiology Polyethylene Terephthalates Prosthesis Design Reoperation Retrospective Studies Time Factors Treatment Outcome |
title | High incidence of Dacron conduit stenosis for extracardiac Fontan procedure |
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