High incidence of Dacron conduit stenosis for extracardiac Fontan procedure

Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no info...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2014-05, Vol.147 (5), p.1568-1572
Hauptverfasser: van Brakel, Thomas J., MD, PhD, Schoof, Paul H., MD, PhD, de Roo, Frank, MPA, Nikkels, Peter G.J., MD, PhD, Evens, Fabiola C.M., MD, Haas, Felix, MD
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container_end_page 1572
container_issue 5
container_start_page 1568
container_title The Journal of thoracic and cardiovascular surgery
container_volume 147
creator van Brakel, Thomas J., MD, PhD
Schoof, Paul H., MD, PhD
de Roo, Frank, MPA
Nikkels, Peter G.J., MD, PhD
Evens, Fabiola C.M., MD
Haas, Felix, MD
description Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.
doi_str_mv 10.1016/j.jtcvs.2013.07.013
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Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (&gt;50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.</description><identifier>ISSN: 0022-5223</identifier><identifier>EISSN: 1097-685X</identifier><identifier>DOI: 10.1016/j.jtcvs.2013.07.013</identifier><identifier>PMID: 23988293</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation - adverse effects ; Blood Vessel Prosthesis Implantation - instrumentation ; Cardiothoracic Surgery ; Child, Preschool ; Constriction, Pathologic ; Device Removal ; Fontan Procedure - adverse effects ; Graft Occlusion, Vascular - diagnosis ; Graft Occlusion, Vascular - epidemiology ; Graft Occlusion, Vascular - surgery ; Heart Defects, Congenital - physiopathology ; Heart Defects, Congenital - surgery ; Humans ; Incidence ; Length of Stay ; Netherlands - epidemiology ; Polyethylene Terephthalates ; Prosthesis Design ; Reoperation ; Retrospective Studies ; Time Factors ; Treatment Outcome</subject><ispartof>The Journal of thoracic and cardiovascular surgery, 2014-05, Vol.147 (5), p.1568-1572</ispartof><rights>The American Association for Thoracic Surgery</rights><rights>2014 The American Association for Thoracic Surgery</rights><rights>Copyright © 2014 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-66064029a1a52e2e3d024b17995e8f10e342e445efdc7d32733d7ea36a96e3173</citedby><cites>FETCH-LOGICAL-c525t-66064029a1a52e2e3d024b17995e8f10e342e445efdc7d32733d7ea36a96e3173</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jtcvs.2013.07.013$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23988293$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van Brakel, Thomas J., MD, PhD</creatorcontrib><creatorcontrib>Schoof, Paul H., MD, PhD</creatorcontrib><creatorcontrib>de Roo, Frank, MPA</creatorcontrib><creatorcontrib>Nikkels, Peter G.J., MD, PhD</creatorcontrib><creatorcontrib>Evens, Fabiola C.M., MD</creatorcontrib><creatorcontrib>Haas, Felix, MD</creatorcontrib><title>High incidence of Dacron conduit stenosis for extracardiac Fontan procedure</title><title>The Journal of thoracic and cardiovascular surgery</title><addtitle>J Thorac Cardiovasc Surg</addtitle><description>Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (&gt;50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.</description><subject>Blood Vessel Prosthesis</subject><subject>Blood Vessel Prosthesis Implantation - adverse effects</subject><subject>Blood Vessel Prosthesis Implantation - instrumentation</subject><subject>Cardiothoracic Surgery</subject><subject>Child, Preschool</subject><subject>Constriction, Pathologic</subject><subject>Device Removal</subject><subject>Fontan Procedure - adverse effects</subject><subject>Graft Occlusion, Vascular - diagnosis</subject><subject>Graft Occlusion, Vascular - epidemiology</subject><subject>Graft Occlusion, Vascular - surgery</subject><subject>Heart Defects, Congenital - physiopathology</subject><subject>Heart Defects, Congenital - surgery</subject><subject>Humans</subject><subject>Incidence</subject><subject>Length of Stay</subject><subject>Netherlands - epidemiology</subject><subject>Polyethylene Terephthalates</subject><subject>Prosthesis Design</subject><subject>Reoperation</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0022-5223</issn><issn>1097-685X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFP3TAQhC1UBK_QX1Cp8rGXhLUdxy-HVqqgFFQkDoDUm2XsTes0z6Z2guDf1-FRDr1wmsvMjvYbQt4zqBmw9mioh8ne55oDEzWousgOWTHoVNWu5Y83ZAXAeSU5F_vkbc4DAChg3R7Z56Jbr3knVuT7mf_5i_pgvcNgkcaenhibYqA2Bjf7ieYJQ8w-0z4mig9TMtYk542lpzFMJtC7FC26OeEh2e3NmPHdsx6Qm9Ov18dn1cXlt_PjLxeVlVxOVdtC2wDvDDOSI0fhgDe3THWdxHXPAEXDsWkk9s4qJ7gSwik0ojVdi4IpcUA-bu-W5j8z5klvfLY4jiZgnLNmkjPRgORQrGJrLS_lnLDXd8lvTHrUDPRCUQ_6iaJeKGpQukhJfXgumG836F4y_7AVw6etAcub9x6TztYv_JxPaCfton-l4PN_eTv64K0Zf-Mj5iHOKRSCmunMNeirZchlRybKhKqR4i9SyJhf</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>van Brakel, Thomas J., MD, PhD</creator><creator>Schoof, Paul H., MD, PhD</creator><creator>de Roo, Frank, MPA</creator><creator>Nikkels, Peter G.J., MD, PhD</creator><creator>Evens, Fabiola C.M., MD</creator><creator>Haas, Felix, MD</creator><general>Mosby, Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140501</creationdate><title>High incidence of Dacron conduit stenosis for extracardiac Fontan procedure</title><author>van Brakel, Thomas J., MD, PhD ; Schoof, Paul H., MD, PhD ; de Roo, Frank, MPA ; Nikkels, Peter G.J., MD, PhD ; Evens, Fabiola C.M., MD ; Haas, Felix, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-66064029a1a52e2e3d024b17995e8f10e342e445efdc7d32733d7ea36a96e3173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Blood Vessel Prosthesis</topic><topic>Blood Vessel Prosthesis Implantation - adverse effects</topic><topic>Blood Vessel Prosthesis Implantation - instrumentation</topic><topic>Cardiothoracic Surgery</topic><topic>Child, Preschool</topic><topic>Constriction, Pathologic</topic><topic>Device Removal</topic><topic>Fontan Procedure - adverse effects</topic><topic>Graft Occlusion, Vascular - diagnosis</topic><topic>Graft Occlusion, Vascular - epidemiology</topic><topic>Graft Occlusion, Vascular - surgery</topic><topic>Heart Defects, Congenital - physiopathology</topic><topic>Heart Defects, Congenital - surgery</topic><topic>Humans</topic><topic>Incidence</topic><topic>Length of Stay</topic><topic>Netherlands - epidemiology</topic><topic>Polyethylene Terephthalates</topic><topic>Prosthesis Design</topic><topic>Reoperation</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van Brakel, Thomas J., MD, PhD</creatorcontrib><creatorcontrib>Schoof, Paul H., MD, PhD</creatorcontrib><creatorcontrib>de Roo, Frank, MPA</creatorcontrib><creatorcontrib>Nikkels, Peter G.J., MD, PhD</creatorcontrib><creatorcontrib>Evens, Fabiola C.M., MD</creatorcontrib><creatorcontrib>Haas, Felix, MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van Brakel, Thomas J., MD, PhD</au><au>Schoof, Paul H., MD, PhD</au><au>de Roo, Frank, MPA</au><au>Nikkels, Peter G.J., MD, PhD</au><au>Evens, Fabiola C.M., MD</au><au>Haas, Felix, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High incidence of Dacron conduit stenosis for extracardiac Fontan procedure</atitle><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle><addtitle>J Thorac Cardiovasc Surg</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>147</volume><issue>5</issue><spage>1568</spage><epage>1572</epage><pages>1568-1572</pages><issn>0022-5223</issn><eissn>1097-685X</eissn><abstract>Objectives Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency. Methods All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (&gt;50% of diameter) underwent reoperation. Results Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days. Conclusions The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>23988293</pmid><doi>10.1016/j.jtcvs.2013.07.013</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation - adverse effects
Blood Vessel Prosthesis Implantation - instrumentation
Cardiothoracic Surgery
Child, Preschool
Constriction, Pathologic
Device Removal
Fontan Procedure - adverse effects
Graft Occlusion, Vascular - diagnosis
Graft Occlusion, Vascular - epidemiology
Graft Occlusion, Vascular - surgery
Heart Defects, Congenital - physiopathology
Heart Defects, Congenital - surgery
Humans
Incidence
Length of Stay
Netherlands - epidemiology
Polyethylene Terephthalates
Prosthesis Design
Reoperation
Retrospective Studies
Time Factors
Treatment Outcome
title High incidence of Dacron conduit stenosis for extracardiac Fontan procedure
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