Distinguishing between mechanisms of cell aggregation using pair-correlation functions

Many cell types form clumps or aggregates when cultured in vitro through a variety of mechanisms including rapid cell proliferation, chemotaxis, or direct cell-to-cell contact. In this paper we develop an agent-based model to explore the formation of aggregates in cultures where cells are initially...

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Veröffentlicht in:	Journal of theoretical biology 2014-07, Vol.352, p.16-23
Hauptverfasser:	Agnew, D.J.G., Green, J.E.F., Brown, T.M., Simpson, M.J., Binder, B.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agent-based model Cell Aggregation Cell Line, Tumor Cell proliferation Cell–cell interaction Humans In Vitro Techniques Models, Biological Spatial patterns
Online-Zugang:	Volltext
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