Laccase and Laccase-Mediated Systems in the Synthesis of Organic Compounds

Laccase, a blue multicopper oxidase, has recently received considerable attention because of its usefulness in oxidizing phenolic and non‐phenolic compounds, as well as its suitability for organic synthesis, environmental pollutant treatment, and other biotechnological applications. This review cove...

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Veröffentlicht in:Advanced synthesis & catalysis 2014-03, Vol.356 (5), p.897-927
Hauptverfasser: Mogharabi, Mehdi, Faramarzi, Mohammad Ali
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description Laccase, a blue multicopper oxidase, has recently received considerable attention because of its usefulness in oxidizing phenolic and non‐phenolic compounds, as well as its suitability for organic synthesis, environmental pollutant treatment, and other biotechnological applications. This review covers recent studies on the structural properties, occurrence, reaction mechnisms, redox mediators of laccases and their application in organic synthesis procedures, such as dimerization, polymerization, oxidation, and amination. We also present a brief discussion on laccase activity in non‐aqueous media. Given that the development of green protocols for the synthesis of pure compounds is one of the main goals of sustainable chemistry, the exploitation of laccases is expected to remain one of the most popular directions in future biocatalysis research.
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subjects biocatalysis
Catalysis
chemical mediators
Exploitation
Laccase
Organic compounds
organic synthesis
Oxidase
Oxidation
Pollutants
Synthesis
title Laccase and Laccase-Mediated Systems in the Synthesis of Organic Compounds
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