In-vivo efficacy of toltrazuril on experimentally induced Toxoplasma gondii tissue cysts in lambs: A novel strategy for prevention of human exposure to meat-borne toxoplasmosis

The aim of the present study was to investigate in vivo efficacy of toltrazuril on Toxoplasma gondii tissue cysts following induction of chronic toxoplasmosis in 4-week-old lambs (n=27) by inoculation of 1×105T. gondii ME 49 strain oocysts (day 0). Beginning at the 15th day after inoculation, lambs...

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Veröffentlicht in:	Research in veterinary science 2013-04, Vol.94 (2), p.269-276
Hauptverfasser:	Kul, Oguz, Yildiz, Kader, Ocal, Naci, Freyre, Alvaro, Deniz, Abdulkerim, Karahan, Siyami, Atmaca, Hasan Tarik, Gokpinar, Sami, Dincel, Gungor Cagdas, Uzunalioğlu, Tuba, Terzi, Osman Safa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antibodies Antibodies, Protozoan - blood brain centrifugation Coccidiostats - therapeutic use Food-borne histopathology Human humans Immunohistochemistry Infections Lamb lambs macrophages Meat - parasitology Microbiology muscles mutton oocysts Parasites polymerase chain reaction Protozoa Serologic Tests seroprevalence Sheep Sheep Diseases - drug therapy therapeutics Time Factors Tissue cyst Toltrazuril Toxoplasma gondii toxoplasmosis Toxoplasmosis, Animal - drug therapy Triazines - therapeutic use Veterinary medicine
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