Effects of developmental hyperserotonemia on juvenile play behavior, oxytocin and serotonin receptor expression in the hypothalamus are age and sex dependent

Abstract There is a striking sex difference in the diagnosis of Autism Spectrum Disorder (ASD), such that males are diagnosed more often than females, usually in early childhood. Given that recent research has implicated elevated blood serotonin (hyperserotonemia) in perinatal development as a poten...

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Veröffentlicht in:	Physiology & behavior 2014-04, Vol.128, p.260-269
Hauptverfasser:	Madden, Amanda M.K, Zup, Susan L
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Autism Behavior, Animal - physiology Behavioral psychophysiology Biological and medical sciences Child clinical studies Developmental disorders Female Fundamental and applied biological sciences. Psychology Hypothalamus Hypothalamus - drug effects Hypothalamus - metabolism Hypothalamus - physiology Infantile autism Juvenile play behavior Male Medical sciences Oxytocin Paraventricular Hypothalamic Nucleus - drug effects Paraventricular Hypothalamic Nucleus - metabolism Paraventricular Hypothalamic Nucleus - physiology Play and Playthings Psychiatry Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychopathology. Psychiatry Rats Rats, Sprague-Dawley - growth & development Receptor, Serotonin, 5-HT2A - biosynthesis Receptor, Serotonin, 5-HT2A - physiology Receptors, Oxytocin - biosynthesis Receptors, Oxytocin - physiology Receptors, Serotonin - biosynthesis Receptors, Serotonin - physiology Serotonin - blood Serotonin - pharmacology Serotonin receptor Sex difference Sex Factors
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