Evidence for contribution of epigenetic mechanisms in the pathogenesis of systemic mast cell activation disease

Recently, evidence was provided for common familial occurrence of systemic mast cell activation disease (MCAD), i.e., mast cell disorders characterized by aberrant release of mast cell mediators and/or accumulation of pathological mast cells in potentially any tissue. Since there is accumulating evi...

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Veröffentlicht in:	Immunogenetics (New York) 2014-05, Vol.66 (5), p.287-297
Hauptverfasser:	Haenisch, Britta, Fröhlich, Holger, Herms, Stefan, Molderings, Gerhard J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Age of Onset Aged Allergology Biomedical and Life Sciences Biomedicine Blood & organ donations Cell Biology Cluster Analysis CpG Islands Deoxyribonucleic acid Disease DNA DNA Methylation Epigenesis, Genetic Epigenetics Female Gene Expression Profiling Gene Function Hospitals Human Genetics Humans Immunology Kinases Leukocytes Male Mast Cells - immunology Mast Cells - metabolism Mast Cells - pathology Mastocytosis - genetics Mastocytosis - immunology Middle Aged Mutation Original Paper Pathogenesis Patients Young Adult
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