Highly efficient one-pot multi-component synthesis of α-aminophosphonates and bis-α-aminophosphonates catalyzed by heterogeneous reusable silica supported dodecatungstophosphoric acid (DTP/SiO2) at ambient temperature and their antitubercular evaluation against Mycobactrium Tuberculosis
A highly efficient one-pot multi-component reaction (MCR) protocol over DTP/SiO sub(2) has been developed for the synthesis of alpha -aminophosphonate derivatives (4a-x) in excellent yields. The alpha -aminophosphonate derivatives were for the first time evaluated for their antitubercular activity a...
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Veröffentlicht in: | RSC advances 2014, Vol.4 (15), p.7666-7672 |
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Sprache: | eng |
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