Highly efficient one-pot multi-component synthesis of α-aminophosphonates and bis-α-aminophosphonates catalyzed by heterogeneous reusable silica supported dodecatungstophosphoric acid (DTP/SiO2) at ambient temperature and their antitubercular evaluation against Mycobactrium Tuberculosis

A highly efficient one-pot multi-component reaction (MCR) protocol over DTP/SiO sub(2) has been developed for the synthesis of alpha -aminophosphonate derivatives (4a-x) in excellent yields. The alpha -aminophosphonate derivatives were for the first time evaluated for their antitubercular activity a...

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Veröffentlicht in:RSC advances 2014, Vol.4 (15), p.7666-7672
Hauptverfasser: Mulla, Shafeek A. R., Pathan, Mohsinkhan Y., Chavan, Santosh S., Gample, Suwara P., Sarkar, Dhiman
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Sprache:eng
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