Genetic variant of AKT1 and AKTIP associated with late-onset depression in a Brazilian population

Objectives Examine the association between polymorphisms in the AKT1 and AKTIP genes and late‐onset depression (LOD). Major depressive disorder is one of the most prevalent neuropsychiatric diseases. LOD is a disorder that starts after 65 years old. AKT1 is a downstream enzyme that has been implicat...

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Veröffentlicht in:	International journal of geriatric psychiatry 2014-04, Vol.29 (4), p.399-405
Hauptverfasser:	Pereira, Patricia Araújo, Bicalho, Maria Aparecida Camargos, de Moraes, Edgar Nunes, Malloy-Diniz, Leandro, Bozzi, Isadora Cristine Reis Sguizzato, Nicolato, Rodrigo, Valadão, Daniela Rosa, Miranda, Debora Marques, Romano-Silva, Marco Aurélio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Age of Onset Aged Aged, 80 and over AKT Interaction Protein (AKTIP) Alleles Apoptosis Regulatory Proteins - genetics Biological and medical sciences Brazil Case-Control Studies Depressive Disorder, Major - genetics Enzymes Female Gene Frequency General aspects Genes Genetic Variation Geriatric psychiatry Geriatrics Humans late-onset depression (LOD) Male Medical sciences Mental depression Older people Pneumology Polymorphism Polymorphism, Genetic Proto-Oncogene Proteins c-akt - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry serotonin (5-HT) single-nucleotide polymorphism (SNP) Tumors of the respiratory system and mediastinum V-akt murine thymoma viral oncogene homolog 1 (AKT1)
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