The spreading process of Ehrlichia canis in macrophages is dependent on actin cytoskeleton, calcium and iron influx and lysosomal evasion

Ehrlichia canis is an obligate intracellular microorganism and the etiologic agent of canine monocytic ehrlichiosis. The invasion process has already been described for some bacteria in this genus, such as E. muris and E. chaffeensis, and consists of four stages: adhesion, internalisation, intracell...

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Veröffentlicht in:	Veterinary microbiology 2014-01, Vol.168 (2-4), p.442-446
Hauptverfasser:	Alves, R.N., Levenhagen, M.A., Levenhagen, M.M.M.D., Rieck, S.E., Labruna, M.B., Beletti, M.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - immunology Actin Cytoskeleton - metabolism Animals Calcium - metabolism Calcium Channel Blockers - pharmacology Canine macrophage Cells, Cultured Cytochalasins - pharmacology Deferoxamine - pharmacology Dog Diseases - drug therapy Dog Diseases - immunology Dog Diseases - microbiology Dogs Ehrlichia canis Ehrlichia canis - drug effects Ehrlichia canis - growth & development Ehrlichia canis - immunology Ehrlichiosis - drug therapy Ehrlichiosis - immunology Ehrlichiosis - veterinary In vitro Iron - metabolism Lysosomes - metabolism Lysosomes - microbiology Lysosomes - ultrastructure Macrophages - metabolism Macrophages - microbiology Macrophages - ultrastructure Microscopy, Electron, Transmission Monocytes - metabolism Monocytes - microbiology Monocytes - ultrastructure Siderophores - pharmacology Spreading Verapamil - pharmacology
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