Inappropriate prescribing in older fallers presenting to an Irish emergency department
certain medications increase falls risk in older people. to assess if prescribing modification occurs in older falls presenting to an emergency department (ED). before-and-after design: presentation to ED with a fall as the index event. over 70's who presented to ED with a fall over a 4-year pe...
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Veröffentlicht in: | Age and ageing 2014-01, Vol.43 (1), p.44-50 |
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creator | McMahon, C Geraldine Cahir, Caitriona A Kenny, Rose Anne Bennett, Kathleen |
description | certain medications increase falls risk in older people.
to assess if prescribing modification occurs in older falls presenting to an emergency department (ED).
before-and-after design: presentation to ED with a fall as the index event.
over 70's who presented to ED with a fall over a 4-year period.
dispensed medication in the 12 months pre- and post-fall was identified using a primary care reimbursement services pharmacy claims database. Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P < 0.05).
One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). A high prevalence of psychotropic medication was identified pre-fall: anxiolytics (15.7%), antidepressants (26%), hypnosedatives (30%). New initiation of anxiolytics and hypnosedatives occurred in 9-15%, respectively, post-fall.
a significant prevalence of PIP was observed in older fallers presenting to the ED. No substantial improvements in PIP occurred in the 12 months post-fall, suggesting the need for focused intervention studies to be undertaken in this area. |
doi_str_mv | 10.1093/ageing/aft114 |
format | Article |
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to assess if prescribing modification occurs in older falls presenting to an emergency department (ED).
before-and-after design: presentation to ED with a fall as the index event.
over 70's who presented to ED with a fall over a 4-year period.
dispensed medication in the 12 months pre- and post-fall was identified using a primary care reimbursement services pharmacy claims database. Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P < 0.05).
One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). A high prevalence of psychotropic medication was identified pre-fall: anxiolytics (15.7%), antidepressants (26%), hypnosedatives (30%). New initiation of anxiolytics and hypnosedatives occurred in 9-15%, respectively, post-fall.
a significant prevalence of PIP was observed in older fallers presenting to the ED. No substantial improvements in PIP occurred in the 12 months post-fall, suggesting the need for focused intervention studies to be undertaken in this area.</description><identifier>ISSN: 0002-0729</identifier><identifier>EISSN: 1468-2834</identifier><identifier>DOI: 10.1093/ageing/aft114</identifier><identifier>PMID: 23927888</identifier><identifier>CODEN: AANGAH</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Accident and emergency departments ; Accidental Falls ; Age Factors ; Aged ; Aged, 80 and over ; Antipsychotic Agents - adverse effects ; Complications and side effects ; Drug Prescriptions ; Drug Utilization Review ; Drugs ; Elderly ; Emergency medical care ; Emergency Medical Services - standards ; Falls ; Falls (Accidents) ; Female ; Geriatric Assessment ; Geriatrics ; Guideline Adherence ; Health aspects ; Humans ; Inappropriate Prescribing ; Inappropriateness ; Insurance, Pharmaceutical Services ; Ireland ; Male ; Medication Reconciliation - standards ; Older people ; Polypharmacy ; Practice Guidelines as Topic ; Practice Patterns, Physicians' - standards ; Prescribing ; Prescription drugs ; Prevalence ; Psychotropic drugs ; Risk Factors ; Time Factors</subject><ispartof>Age and ageing, 2014-01, Vol.43 (1), p.44-50</ispartof><rights>Copyright Oxford Publishing Limited(England) Jan 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c497t-f318417a77c3bb38d736d1c384c96f2183901fffb4c18e76585213d4efe7ca323</citedby><cites>FETCH-LOGICAL-c497t-f318417a77c3bb38d736d1c384c96f2183901fffb4c18e76585213d4efe7ca323</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906,30980,30981</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23927888$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McMahon, C Geraldine</creatorcontrib><creatorcontrib>Cahir, Caitriona A</creatorcontrib><creatorcontrib>Kenny, Rose Anne</creatorcontrib><creatorcontrib>Bennett, Kathleen</creatorcontrib><title>Inappropriate prescribing in older fallers presenting to an Irish emergency department</title><title>Age and ageing</title><addtitle>Age Ageing</addtitle><description>certain medications increase falls risk in older people.
to assess if prescribing modification occurs in older falls presenting to an emergency department (ED).
before-and-after design: presentation to ED with a fall as the index event.
over 70's who presented to ED with a fall over a 4-year period.
dispensed medication in the 12 months pre- and post-fall was identified using a primary care reimbursement services pharmacy claims database. Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P < 0.05).
One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). A high prevalence of psychotropic medication was identified pre-fall: anxiolytics (15.7%), antidepressants (26%), hypnosedatives (30%). New initiation of anxiolytics and hypnosedatives occurred in 9-15%, respectively, post-fall.
a significant prevalence of PIP was observed in older fallers presenting to the ED. No substantial improvements in PIP occurred in the 12 months post-fall, suggesting the need for focused intervention studies to be undertaken in this area.</description><subject>Accident and emergency departments</subject><subject>Accidental Falls</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antipsychotic Agents - adverse effects</subject><subject>Complications and side effects</subject><subject>Drug Prescriptions</subject><subject>Drug Utilization Review</subject><subject>Drugs</subject><subject>Elderly</subject><subject>Emergency medical care</subject><subject>Emergency Medical Services - standards</subject><subject>Falls</subject><subject>Falls (Accidents)</subject><subject>Female</subject><subject>Geriatric Assessment</subject><subject>Geriatrics</subject><subject>Guideline Adherence</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Inappropriate Prescribing</subject><subject>Inappropriateness</subject><subject>Insurance, Pharmaceutical Services</subject><subject>Ireland</subject><subject>Male</subject><subject>Medication Reconciliation - standards</subject><subject>Older people</subject><subject>Polypharmacy</subject><subject>Practice Guidelines as Topic</subject><subject>Practice Patterns, Physicians' - standards</subject><subject>Prescribing</subject><subject>Prescription drugs</subject><subject>Prevalence</subject><subject>Psychotropic drugs</subject><subject>Risk Factors</subject><subject>Time Factors</subject><issn>0002-0729</issn><issn>1468-2834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqNkc1v1DAQxS0EotvCkSuKxIVLqMcfsX2sVoWuVKkX4Go5zjikSpxgeyX63-OyBSROnEaj-c3TvHmEvAH6Aajhl27EKY6XLhQA8YzsQHS6ZZqL52RHKWUtVcyckfOc72sLEthLcsa4YUprvSNfD9FtW1q3NLmCzZYw-zT1VbKZYrPOA6YmuHnGlH8NMZbHWVkbF5tDmvK3BhdMI0b_0Ay4uVSWyrwiL-pWxtdP9YJ8-Xj9eX_T3t59OuyvblsvjCpt4KAFKKeU533P9aB4N4DnWnjTBQaaGwohhF540Kg6qSUDPggMqLzjjF-Q9yfdauH7EXOxy5Q9zrOLuB6zBckoZx2Y_0CFUlKyznQVffcPer8eU6xGqqCQktfjdaXaEzW6Ge0U_RoL_ih-rd8a0Vaf-zt7xTsljdRU_eV9WnNOGGx9-uLSgwVqH7O0pyztKcvKv3264tgvOPyhf4fHfwJcupqe</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>McMahon, C Geraldine</creator><creator>Cahir, Caitriona A</creator><creator>Kenny, Rose Anne</creator><creator>Bennett, Kathleen</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20140101</creationdate><title>Inappropriate prescribing in older fallers presenting to an Irish emergency department</title><author>McMahon, C Geraldine ; Cahir, Caitriona A ; Kenny, Rose Anne ; Bennett, Kathleen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c497t-f318417a77c3bb38d736d1c384c96f2183901fffb4c18e76585213d4efe7ca323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Accident and emergency departments</topic><topic>Accidental Falls</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antipsychotic Agents - adverse effects</topic><topic>Complications and side effects</topic><topic>Drug Prescriptions</topic><topic>Drug Utilization Review</topic><topic>Drugs</topic><topic>Elderly</topic><topic>Emergency medical care</topic><topic>Emergency Medical Services - standards</topic><topic>Falls</topic><topic>Falls (Accidents)</topic><topic>Female</topic><topic>Geriatric Assessment</topic><topic>Geriatrics</topic><topic>Guideline Adherence</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Inappropriate Prescribing</topic><topic>Inappropriateness</topic><topic>Insurance, Pharmaceutical Services</topic><topic>Ireland</topic><topic>Male</topic><topic>Medication Reconciliation - standards</topic><topic>Older people</topic><topic>Polypharmacy</topic><topic>Practice Guidelines as Topic</topic><topic>Practice Patterns, Physicians' - standards</topic><topic>Prescribing</topic><topic>Prescription drugs</topic><topic>Prevalence</topic><topic>Psychotropic drugs</topic><topic>Risk Factors</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McMahon, C Geraldine</creatorcontrib><creatorcontrib>Cahir, Caitriona A</creatorcontrib><creatorcontrib>Kenny, Rose Anne</creatorcontrib><creatorcontrib>Bennett, Kathleen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Age and ageing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McMahon, C Geraldine</au><au>Cahir, Caitriona A</au><au>Kenny, Rose Anne</au><au>Bennett, Kathleen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inappropriate prescribing in older fallers presenting to an Irish emergency department</atitle><jtitle>Age and ageing</jtitle><addtitle>Age Ageing</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>43</volume><issue>1</issue><spage>44</spage><epage>50</epage><pages>44-50</pages><issn>0002-0729</issn><eissn>1468-2834</eissn><coden>AANGAH</coden><abstract>certain medications increase falls risk in older people.
to assess if prescribing modification occurs in older falls presenting to an emergency department (ED).
before-and-after design: presentation to ED with a fall as the index event.
over 70's who presented to ED with a fall over a 4-year period.
dispensed medication in the 12 months pre- and post-fall was identified using a primary care reimbursement services pharmacy claims database. Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P < 0.05).
One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). A high prevalence of psychotropic medication was identified pre-fall: anxiolytics (15.7%), antidepressants (26%), hypnosedatives (30%). New initiation of anxiolytics and hypnosedatives occurred in 9-15%, respectively, post-fall.
a significant prevalence of PIP was observed in older fallers presenting to the ED. No substantial improvements in PIP occurred in the 12 months post-fall, suggesting the need for focused intervention studies to be undertaken in this area.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>23927888</pmid><doi>10.1093/ageing/aft114</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Accident and emergency departments Accidental Falls Age Factors Aged Aged, 80 and over Antipsychotic Agents - adverse effects Complications and side effects Drug Prescriptions Drug Utilization Review Drugs Elderly Emergency medical care Emergency Medical Services - standards Falls Falls (Accidents) Female Geriatric Assessment Geriatrics Guideline Adherence Health aspects Humans Inappropriate Prescribing Inappropriateness Insurance, Pharmaceutical Services Ireland Male Medication Reconciliation - standards Older people Polypharmacy Practice Guidelines as Topic Practice Patterns, Physicians' - standards Prescribing Prescription drugs Prevalence Psychotropic drugs Risk Factors Time Factors |
title | Inappropriate prescribing in older fallers presenting to an Irish emergency department |
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