Inappropriate prescribing in older fallers presenting to an Irish emergency department

certain medications increase falls risk in older people. to assess if prescribing modification occurs in older falls presenting to an emergency department (ED). before-and-after design: presentation to ED with a fall as the index event. over 70's who presented to ED with a fall over a 4-year pe...

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Veröffentlicht in:Age and ageing 2014-01, Vol.43 (1), p.44-50
Hauptverfasser: McMahon, C Geraldine, Cahir, Caitriona A, Kenny, Rose Anne, Bennett, Kathleen
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container_end_page 50
container_issue 1
container_start_page 44
container_title Age and ageing
container_volume 43
creator McMahon, C Geraldine
Cahir, Caitriona A
Kenny, Rose Anne
Bennett, Kathleen
description certain medications increase falls risk in older people. to assess if prescribing modification occurs in older falls presenting to an emergency department (ED). before-and-after design: presentation to ED with a fall as the index event. over 70's who presented to ED with a fall over a 4-year period. dispensed medication in the 12 months pre- and post-fall was identified using a primary care reimbursement services pharmacy claims database. Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P < 0.05). One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). A high prevalence of psychotropic medication was identified pre-fall: anxiolytics (15.7%), antidepressants (26%), hypnosedatives (30%). New initiation of anxiolytics and hypnosedatives occurred in 9-15%, respectively, post-fall. a significant prevalence of PIP was observed in older fallers presenting to the ED. No substantial improvements in PIP occurred in the 12 months post-fall, suggesting the need for focused intervention studies to be undertaken in this area.
doi_str_mv 10.1093/ageing/aft114
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Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P &lt; 0.05). One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). 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Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P &lt; 0.05). One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). 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Cahir, Caitriona A ; Kenny, Rose Anne ; Bennett, Kathleen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c497t-f318417a77c3bb38d736d1c384c96f2183901fffb4c18e76585213d4efe7ca323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Accident and emergency departments</topic><topic>Accidental Falls</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antipsychotic Agents - adverse effects</topic><topic>Complications and side effects</topic><topic>Drug Prescriptions</topic><topic>Drug Utilization Review</topic><topic>Drugs</topic><topic>Elderly</topic><topic>Emergency medical care</topic><topic>Emergency Medical Services - standards</topic><topic>Falls</topic><topic>Falls (Accidents)</topic><topic>Female</topic><topic>Geriatric Assessment</topic><topic>Geriatrics</topic><topic>Guideline Adherence</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Inappropriate Prescribing</topic><topic>Inappropriateness</topic><topic>Insurance, Pharmaceutical Services</topic><topic>Ireland</topic><topic>Male</topic><topic>Medication Reconciliation - standards</topic><topic>Older people</topic><topic>Polypharmacy</topic><topic>Practice Guidelines as Topic</topic><topic>Practice Patterns, Physicians' - standards</topic><topic>Prescribing</topic><topic>Prescription drugs</topic><topic>Prevalence</topic><topic>Psychotropic drugs</topic><topic>Risk Factors</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McMahon, C Geraldine</creatorcontrib><creatorcontrib>Cahir, Caitriona A</creatorcontrib><creatorcontrib>Kenny, Rose Anne</creatorcontrib><creatorcontrib>Bennett, Kathleen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index &amp; 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Screening Tool of Older Person's PIP (STOPP) and Beers prescribing criteria were applied to identify potentially inappropriate prescribing (PIP). Polypharmacy was defined as four or more regular medicines. Psychotropic medication was identified using the WHO Anatomical Therapeutic Chemical classification system. Changes in prescribing were compared using McNemar's test (significance P &lt; 0.05). One thousand sixteen patients were eligible for analysis; 53.1% had at least one STOPP criteria pre-fall with no change post-fall (53.7%, P = 0.64). Beers criteria were identified in 44.0% pre-fall, with no change post-fall (41.5%, P = 0.125). The most significant individual indicators to change were neuroleptics, which decreased from 17.5 to 14.7% (P = 0.02) and long-acting benzodiazepines decreased from 10.7 to 8.6% (P = 0.005). Polypharmacy was observed in 63% and was strongly predictive of PIP, OR 4.0 (95% CI 3.0, 5.32). A high prevalence of psychotropic medication was identified pre-fall: anxiolytics (15.7%), antidepressants (26%), hypnosedatives (30%). New initiation of anxiolytics and hypnosedatives occurred in 9-15%, respectively, post-fall. a significant prevalence of PIP was observed in older fallers presenting to the ED. No substantial improvements in PIP occurred in the 12 months post-fall, suggesting the need for focused intervention studies to be undertaken in this area.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>23927888</pmid><doi>10.1093/ageing/aft114</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Accident and emergency departments
Accidental Falls
Age Factors
Aged
Aged, 80 and over
Antipsychotic Agents - adverse effects
Complications and side effects
Drug Prescriptions
Drug Utilization Review
Drugs
Elderly
Emergency medical care
Emergency Medical Services - standards
Falls
Falls (Accidents)
Female
Geriatric Assessment
Geriatrics
Guideline Adherence
Health aspects
Humans
Inappropriate Prescribing
Inappropriateness
Insurance, Pharmaceutical Services
Ireland
Male
Medication Reconciliation - standards
Older people
Polypharmacy
Practice Guidelines as Topic
Practice Patterns, Physicians' - standards
Prescribing
Prescription drugs
Prevalence
Psychotropic drugs
Risk Factors
Time Factors
title Inappropriate prescribing in older fallers presenting to an Irish emergency department
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